Large-Scale de novo Oligonucleotide Synthesis for Whole-Genome Synthesis and Data Storage: Challenges and Opportunities

LF Song, ZH Deng, ZY Gong, LL Li… - Frontiers in bioengineering …, 2021 - frontiersin.org
Over the past decades, remarkable progress on phosphoramidite chemistry-based large-
scale de novo oligonucleotide synthesis has been achieved, enabling numerous novel and …

Data storage in DNA with fewer synthesis cycles using composite DNA letters

L Anavy, I Vaknin, O Atar, R Amit, Z Yakhini - Nature biotechnology, 2019 - nature.com
The density and long-term stability of DNA make it an appealing storage medium,
particularly for long-term data archiving. Existing DNA storage technologies involve the …

DNA-based storage: Trends and methods

SMHT Yazdi, HM Kiah, E Garcia-Ruiz… - … , Biological and Multi …, 2015 - ieeexplore.ieee.org
We provide an overview of current approaches to DNA-based storage system design and of
accompanying synthesis, sequencing and editing methods. We also introduce and analyze …

DNA-based data storage systems: A review of implementations and code constructions

O Milenkovic, C Pan - IEEE Transactions on Communications, 2024 - ieeexplore.ieee.org
This invited review paper has the aim to acquaint the communication theory community with
the emerging topic of molecular data storage. The exposition includes an overview of basic …

Rewritable two-dimensional DNA-based data storage with machine learning reconstruction

C Pan, SK Tabatabaei, SMH Tabatabaei Yazdi… - Nature …, 2022 - nature.com
DNA-based data storage platforms traditionally encode information only in the nucleotide
sequence of the molecule. Here we report on a two-dimensional molecular data storage …

Codes for DNA sequence profiles

HM Kiah, GJ Puleo, O Milenkovic - IEEE Transactions on …, 2016 - ieeexplore.ieee.org
We consider the problem of storing and retrieving information from synthetic DNA media. We
introduce the DNA storage channel and model the read process through the use of profile …

Designing uncorrelated address constrain for DNA storage by DMVO algorithm

B Cao, X Ii, X Zhang, B Wang… - … /ACM transactions on …, 2020 - ieeexplore.ieee.org
At present, huge amounts of data are being produced every second, a situation that will
gradually overwhelm current storage technology. DNA is a storage medium that features …

Digital data storage on DNA tape using CRISPR base editors

A Sadremomtaz, RF Glass, JE Guerrero… - Nature …, 2023 - nature.com
While the archival digital memory industry approaches its physical limits, the demand is
significantly increasing, therefore alternatives emerge. Recent efforts have demonstrated …

Design of constraint coding sets for archive DNA storage

Q Yin, Y Zheng, B Wang… - IEEE/ACM transactions on …, 2021 - ieeexplore.ieee.org
With the advent of the era of massive data, the increase of storage demand has far
exceeded current storage capacity. DNA molecules provide a reliable solution for big data …

Exact reconstruction from insertions in synchronization codes

F Sala, R Gabrys, C Schoeny… - IEEE Transactions on …, 2017 - ieeexplore.ieee.org
This paper studies problems in data reconstruction, an important area with numerous
applications. In particular, we examine the reconstruction of binary and nonbinary …