Extracellular vesicles in parasitic diseases–from pathogenesis to future diagnostic tools

SA Menezes, T Tasca - Microbes and Infection, 2024 - Elsevier
Parasitic diseases are still a major public health problem especially among individuals of
low socioeconomic status in underdeveloped countries. In recent years it has been …

Extracellular vesicles released by anaerobic protozoan parasites: Current situation

YR Nievas, A Lizarraga, N Salas… - Cellular …, 2020 - Wiley Online Library
Extracellular vesicles (EVs) have emerged as a ubiquitous mechanism for transferring
information between cells and organisms across all three kingdoms of life. Parasitic …

Immunomodulatory effect of extracellular vesicles from Entamoeba histolytica trophozoites: Regulation of NETs and respiratory burst during confrontation with human …

C Díaz-Godínez, DG Ríos-Valencia… - Frontiers in Cellular …, 2022 - frontiersin.org
Parasites release extracellular vesicles (EVs) which, in some cases, modulate the host's
immune response contributing to the establishment of the infection. In this work we have …

Characterization of extracellular vesicles from Entamoeba histolytica identifies roles in intercellular communication that regulates parasite growth and development

M Sharma, P Morgado, H Zhang… - Infection and …, 2020 - journals.asm.org
Extracellular vesicles (EVs) secreted by eukaryotic and prokaryotic cells to transport lipids,
proteins, and nucleic acids to the external environment have important roles in cell-cell …

Tetraspanin-enriched microdomains play an important role in pathogenesis in the protozoan parasite Entamoeba histolytica

H Jiang, HJ Santos, T Nozaki - PLoS pathogens, 2024 - journals.plos.org
Tetraspanins (TSPANs) are a family of highly conserved proteins present in a wide variety of
eukaryotes. Although protein-protein interactions of TSPANs have been well established in …

Transcriptomic features of Echinococcus granulosus protoscolex during the encystation process

J Fan, H Wu, K Li, X Liu, Q Tan, W Cao… - The Korean journal …, 2020 - pmc.ncbi.nlm.nih.gov
Cystic echinococcosis (CE) is a zoonotic infection caused by Echinococcus granulosus
larvae. It seriously affects the development of animal husbandry and endangers human …

Entamoeba histolytica EHD1 is involved in mitosome-endosome contact

HJ Santos, Y Hanadate, K Imai, H Watanabe, T Nozaki - MBio, 2022 - journals.asm.org
Interorganellar cross talk is often mediated by membrane contact sites (MCSs), which are
zones where participating membranes come within 30 nm of one another. MCSs have been …

Molecular characterization and B-cell epitope analysis of the TSP11 gene in Echinococcus infection strains from Yunnan Province

Q Xu, Z Wang, J Zi, X Cai, F Wu, B Li, J Peng, J Li… - Parasitology, 2024 - cambridge.org
This study investigates the molecular intricacies of the transmembrane protein TSP11 gene
in Echinococcus strains isolated from livestock and patients in Yunnan Province afflicted …

Entamoeba histolytica extracellular vesicles drive pro-inflammatory monocyte signaling

B Honecker, VA Bärreiter, K Höhn, B Horváth, K Harant… - bioRxiv, 2024 - biorxiv.org
The parasitic protozoan Entamoeba histolytica secretes extracellular vesicles (EVs), but so
far little is known about their function in the interaction with the host immune system …

[HTML][HTML] Import of Entamoeba histolytica mitosomal ATP sulfurylase relies on internal targeting sequences

HJ Santos, Y Chiba, T Makiuchi, S Arakawa… - Microorganisms, 2020 - mdpi.com
Mitochondrial matrix proteins synthesized in the cytosol often contain amino (N)-terminal
targeting sequences (NTSs), or alternately internal targeting sequences (ITSs), which …