miRNAs role in bladder cancer pathogenesis and targeted therapy: signaling pathways interplay–a review
Bladder cancer (BC) is the 11th most popular cancer in females and 4th in males. A lot of
efforts have been exerted to improve BC patients' care. Besides, new approaches have …
efforts have been exerted to improve BC patients' care. Besides, new approaches have …
Hallmarks and biomarkers of skin senescence: An updated review of skin senotherapeutics
Aging is a complex process characterized by an ongoing decline in physiological functions,
leading to degenerative diseases and an increased probability of death. Cellular …
leading to degenerative diseases and an increased probability of death. Cellular …
Explore the effect of the structure-activity relationship and dose-effect relationship on the antioxidant activity of licorice flavonoids
Y Hu, P Liang, Z Wang, CP Jiang, Q Zeng… - Journal of Molecular …, 2023 - Elsevier
Licorice flavonoids (LCF) are one of the homologous substances of medicine and food,
which have good antioxidant activity. However, the molecular mechanism affecting its …
which have good antioxidant activity. However, the molecular mechanism affecting its …
Crosstalk between oxidative stress and aging in neurodegeneration disorders
RF Abdelhamid, S Nagano - Cells, 2023 - mdpi.com
The world population is aging rapidly, and increasing lifespan exacerbates the burden of
age-related health issues. On the other hand, premature aging has begun to be a problem …
age-related health issues. On the other hand, premature aging has begun to be a problem …
[HTML][HTML] The redox-responsive roles of intermediate filaments in cellular stress detection, integration and mitigation
Intermediate filaments are critical for cell and tissue homeostasis and for stress responses.
Cytoplasmic intermediate filaments form versatile and dynamic assemblies that interconnect …
Cytoplasmic intermediate filaments form versatile and dynamic assemblies that interconnect …
[HTML][HTML] Mitochondria pleiotropism in stem cell senescence: Mechanisms and therapeutic approaches
C Mas-Bargues - Free Radical Biology and Medicine, 2023 - Elsevier
Aging is a complex biological process characterized by a progressive decline in cellular and
tissue function, ultimately leading to organismal aging. Stem cells, with their regenerative …
tissue function, ultimately leading to organismal aging. Stem cells, with their regenerative …
Oxidative stress and cell senescence as drivers of ageing: Chicken and egg
T von Zglinicki - Ageing Research Reviews, 2024 - Elsevier
Oxidative stress and cell senescence are both important drivers of ageing and age-
associated disease and disability. In vitro, they are closely interconnected in a chicken-and …
associated disease and disability. In vitro, they are closely interconnected in a chicken-and …
Natural bioactive compounds in the management of periodontal diseases: a comprehensive review
Periodontal diseases, chronic inflammatory conditions affecting oral health, are primarily
driven by microbial plaque biofilm and the body's inflammatory response, leading to tissue …
driven by microbial plaque biofilm and the body's inflammatory response, leading to tissue …
Mitochondrial aging and senolytic natural products with protective potential
A Deledda, E Giordano, F Velluzzi, G Flore… - International Journal of …, 2022 - mdpi.com
Living organisms do not disregard the laws of thermodynamics and must therefore consume
energy for their survival. In this way, cellular energy exchanges, which aim above all at the …
energy for their survival. In this way, cellular energy exchanges, which aim above all at the …
Single-cell and spatial RNA sequencing reveal the spatiotemporal trajectories of fruit senescence
X Li, B Li, S Gu, X Pang, P Mason, J Yuan, J Jia… - Nature …, 2024 - nature.com
The senescence of fruit is a complex physiological process, with various cell types within the
pericarp, making it highly challenging to elucidate their individual roles in fruit senescence …
pericarp, making it highly challenging to elucidate their individual roles in fruit senescence …