Macroautophagy is a lysosomal degradative pathway or recycling process that maintains
cellular homeostasis. This autophagy involves a series of sequential processing events …

Regardless of the recent advances in therapeutic developments, cancer is still among the
primary causes of death globally, indicating the need for alternative therapeutic strategies …

Recent studies demonstrated that mitochondrial antioxidant MnSOD that reduces
mitochondrial (mito) reactive oxygen species (ROS) helps maintain an optimal balance …

Mesenchymal stem cell (MSC)-based therapy has emerged as a novel strategy to treat many
degenerative diseases. Accumulating evidence shows that the function of MSCs declines …

Parkinson's disease is a neurodegenerative disorder with a multifactorial aetiology.
Nevertheless, the genetic predisposition in many families with multi-incidence disease …

Blood brain barrier (BBB) breakdown is a key driver of traumatic brain injury (TBI),
contributing to prolonged neurological deficits and increased risk of death in TBI patients …

Primary mitochondrial diseases (PMD) refer to a group of severe, often inherited genetic
conditions due to mutations in the mitochondrial genome or in the nuclear genes encoding …

Apigenin, a flavonoid isolated from plants, provides protection against non-alcoholic fatty
liver disease. However, the mechanism by which apigenin decreases lipid accumulation in …

Inherited metabolic disorders (IMDs) are genetic disorders that cause a disruption of a
specific metabolic pathway leading to biochemical, clinical and pathophysiological …

The emetic syndrome of Bacillus cereus is a food intoxication caused by cereulide (CER)
and manifested by emesis, nausea and in most severe cases with liver failure. While acute …