Albumin conjugates and assemblies as versatile bio-functional additives and carriers for biomedical applications

C Tao, YJ Chuah, C Xu, DA Wang - Journal of Materials Chemistry B, 2019 - pubs.rsc.org
As the most abundant plasma protein, serum albumin has been extensively studied and
employed for therapeutic applications. Despite its direct clinical use for the maintenance of …

A starting point for fluorescence-based single-molecule measurements in biomolecular research

A Gust, A Zander, A Gietl, P Holzmeister, S Schulz… - Molecules, 2014 - mdpi.com
Single-molecule fluorescence techniques are ideally suited to provide information about the
structure-function-dynamics relationship of a biomolecule as static and dynamic …

Hydrophobic fluorescent probes introduce artifacts into single molecule tracking experiments due to non-specific binding

LC Zanetti-Domingues, CJ Tynan, DJ Rolfe, DT Clarke… - PloS one, 2013 - journals.plos.org
Single-molecule techniques are powerful tools to investigate the structure and dynamics of
macromolecular complexes; however, data quality can suffer because of weak specific …

Solid immersion microscopy images cells under cryogenic conditions with 12 nm resolution

L Wang, B Bateman, LC Zanetti-Domingues… - Communications …, 2019 - nature.com
Super-resolution fluorescence microscopy plays a crucial role in our understanding of cell
structure and function by reporting cellular ultrastructure with 20–30 nm resolution. However …

Ultrahigh sensitivity assays for human cardiac troponin I using TiO 2 nanotube arrays

P Kar, A Pandey, JJ Greer, K Shankar - Lab on a Chip, 2012 - pubs.rsc.org
Rapid, highly sensitive troponin assays for the analysis of serum at the point-of-care are
particularly desirable for the effective treatment of myocardial infarction (MYI). TiO2 …

Biocompatible and antifouling coating of cell membrane phosphorylcholine and mussel catechol modified multi-arm PEGs

Y Dang, M Quan, CM **ng, YB Wang… - Journal of Materials …, 2015 - pubs.rsc.org
The design and easy fabrication of biocompatible and antifouling coatings on different
materials are extremely important for biotechnological and biomedical devices. Here we …

Self‐Assembly of Soft Cellulose Nanospheres into Colloidal Gel Layers with Enhanced Protein Adsorption Capability for Next‐Generation Immunoassays

K Solin, M Beaumont, S Rosenfeldt, H Orelma… - Small, 2020 - Wiley Online Library
Soft cationic core/shell cellulose nanospheres can deform and interpenetrate allowing their
self‐assembly into densely packed colloidal nanogel layers. Taking advantage of their water …

Versatile protein nanogels prepared by in situ polymerization

Y Ye, J Yu, Z Gu - Macromolecular Chemistry and Physics, 2016 - Wiley Online Library
Proteins with unique structure and function have tremendous applications for cancer
treatment, vaccination, diagnosis, regenerative medicine, and therapies for loss‐of‐function …

Molecules and methods for iterative polypeptide analysis and processing

JJ Havranek, B Borgo - US Patent 9,435,810, 2016 - Google Patents
Reagents and methods for the digital analysis of proteins or peptides are provided.
Specifically provided herein are proteins for identifying the N-terminal amino acid or N …

A systematic investigation of differential effects of cell culture substrates on the extent of artifacts in single-molecule tracking

LC Zanetti-Domingues, ML Martin-Fernandez… - 2012 - journals.plos.org
Single-molecule techniques are being increasingly applied to biomedical investigation,
notwithstanding the numerous challenges they pose in terms of signal-to-noise ratio issues …