Uric acid in metabolic syndrome: does uric acid have a definitive role?
Increased serum uric acid (SUA) levels are commonly seen in patients with metabolic
syndrome and are widely accepted as risk factors for hypertension, gout, non-alcoholic fatty …
syndrome and are widely accepted as risk factors for hypertension, gout, non-alcoholic fatty …
New insights into purine metabolism in metabolic diseases: role of xanthine oxidoreductase activity
M Furuhashi - American Journal of Physiology …, 2020 - journals.physiology.org
Xanthine oxidoreductase (XOR) consists of two different forms, xanthine dehydrogenase
and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from …
and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from …
Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome
How intestinal microbes regulate metabolic syndrome is incompletely understood. We show
that intestinal microbiota protects against development of obesity, metabolic syndrome, and …
that intestinal microbiota protects against development of obesity, metabolic syndrome, and …
[HTML][HTML] Association of risk factors with type 2 diabetes: A systematic review
Diabetes is the leading cause of severe health complications and one of the top 10 causes
of death worldwide. To date, diabetes has no cure, and therefore, it is necessary to take …
of death worldwide. To date, diabetes has no cure, and therefore, it is necessary to take …
Sugar and artificially sweetened beverages and risk of obesity, type 2 diabetes mellitus, hypertension, and all-cause mortality: a dose–response meta-analysis of …
P Qin, Q Li, Y Zhao, Q Chen, X Sun, Y Liu, H Li… - European journal of …, 2020 - Springer
Although consumption of sugar-sweetened beverages (SSBs) and artificially sweetened
beverages (ASBs) has increasingly been linked with obesity, type 2 diabetes mellitus …
beverages (ASBs) has increasingly been linked with obesity, type 2 diabetes mellitus …
The small intestine converts dietary fructose into glucose and organic acids
Excessive consumption of sweets is a risk factor for metabolic syndrome. A major chemical
feature of sweets is fructose. Despite strong ties between fructose and disease, the …
feature of sweets is fructose. Despite strong ties between fructose and disease, the …
The role of oxidative stress in hyperuricemia and xanthine oxidoreductase (XOR) inhibitors
N Liu, H Xu, Q Sun, X Yu, W Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …
Fructose and sugar: A major mediator of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome; its rising prevalence parallels the rise in obesity and diabetes. Historically …
syndrome; its rising prevalence parallels the rise in obesity and diabetes. Historically …
Empagliflozin effectively lowers liver fat content in well-controlled type 2 diabetes: a randomized, double-blind, phase 4, placebo-controlled trial
S Kahl, S Gancheva, K Straßburger, C Herder… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE To evaluate whether the sodium–glucose cotransporter 2 inhibitor
empagliflozin (EMPA) reduces liver fat content (LFC) in recent-onset and metabolically well …
empagliflozin (EMPA) reduces liver fat content (LFC) in recent-onset and metabolically well …
Hyperuricemia, acute and chronic kidney disease, hypertension, and cardiovascular disease: report of a scientific workshop organized by the National Kidney …
Urate is a cause of gout, kidney stones, and acute kidney injury from tumor lysis syndrome,
but its relationship to kidney disease, cardiovascular disease, and diabetes remains …
but its relationship to kidney disease, cardiovascular disease, and diabetes remains …