Photodynamic therapy (PDT) is a long known, FDA approved, and highly promising
therapeutic modality, which is still develo**. Photosensitizers (PSs) are at the core of PDT …

Nuclear speckles, also known as interchromatin granule clusters, are nuclear domains
enriched in pre-mRNA splicing factors, located in the interchromatin regions of the …

The World of the Cell continúa la tradición de ediciones anteriores ampliamente elogiadas
por cubrir algunos de los conceptos más difíciles: bioenergética, metabolismo, cinética …

The nucleus is highly organized, such that factors involved in the transcription and
processing of distinct classes of RNA are confined within specific nuclear bodies,. One …

In response to environmental stress, the related RNA-binding proteins TIA-1 and TIAR
colocalize with poly (A) RNA at cytoplasmic foci that resemble the stress granules (SGs) that …

It is clear now that eukaryotic cells contain numerous membrane-less organelles, many of
which are formed in response to changes in the cellular environment. Being typically liquid …

Speckles are subnuclear structures that are enriched in pre-messenger RNA splicing factors
and are located in the interchromatin regions of the nucleoplasm of mammalian cells. At the …

The processing of pre-mRNAs is a fundamental step required for the expression of most
metazoan genes. Members of the family of serine/arginine (SR)-rich proteins are critical …

Spinal muscular atrophy (SMA) is a common, often fatal, autosomal recessive disease
leading to progressive muscle wasting and paralysis as a result of degeneration of anterior …

We have developed an inducible system to visualize gene expression at the levels of DNA,
RNA and protein in living cells. The system is composed of a 200 copy transgene array …