An update on pharmacological potential of boswellic acids against chronic diseases
Natural compounds, in recent years, have attracted significant attention for their use in the
prevention and treatment of diverse chronic diseases as they are devoid of major toxicities …
prevention and treatment of diverse chronic diseases as they are devoid of major toxicities …
[HTML][HTML] Selective autophagy regulates cell cycle in cancer therapy
Aberrant function of cell cycle regulators results in uncontrolled cell proliferation, making
them attractive therapeutic targets in cancer treatment. Indeed, survival of many cancers …
them attractive therapeutic targets in cancer treatment. Indeed, survival of many cancers …
Regulation and function of autophagy in pancreatic cancer
Oncogenic KRAS mutation-driven pancreatic ductal adenocarcinoma is currently the fourth-
leading cause of cancer-related deaths in the United States. Macroautophagy (hereafter …
leading cause of cancer-related deaths in the United States. Macroautophagy (hereafter …
MicroRNA-18a-5p functions as an oncogene by directly targeting IRF2 in lung cancer
Lung cancer is the major form of cancer resulting in cancer-related mortality around the
world. MicroRNAs are endogenous small non-coding single-stranded RNAs, which can …
world. MicroRNAs are endogenous small non-coding single-stranded RNAs, which can …
[HTML][HTML] Anti-proliferative and anti-metastatic potential of curcumin analogue, pentagamavunon-1 (PGV-1), toward highly metastatic breast cancer cells in correlation …
Purpose: Pentagamavunon-1 (PGV-1) is a curcumin analogue that shows cytotoxic activity
in various cancer cells. In this study, we evaluated the effect of PGV-1 on a highly metastatic …
in various cancer cells. In this study, we evaluated the effect of PGV-1 on a highly metastatic …
Nifuroxazide boosts the anticancer efficacy of palbociclib-induced senescence by dual inhibition of STAT3 and CDK2 in triple-negative breast cancer
X Wang, W Shi, X Wang, JJ Lu, P He, H Zhang… - Cell Death …, 2023 - nature.com
Though palbociclib, a cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitor has been
approved for treating breast cancer, two major clinical challenges remain:(i) Triple-negative …
approved for treating breast cancer, two major clinical challenges remain:(i) Triple-negative …
Laser activatable nanographene colloids for chemo-photothermal combined gene therapy of triple-negative breast cancer
This investigation reports the green approach for develo** laser activatable nanoscale-
graphene colloids (nGC-CO-FA) for chemo-photothermal combined gene therapy of triple …
graphene colloids (nGC-CO-FA) for chemo-photothermal combined gene therapy of triple …
Cannabidiol Antiproliferative Effect in Triple-Negative breast Cancer MDA-MB-231 cells is modulated by its physical state and by IGF-1
Cannabidiol (CBD) is a non-psychoactive phytocannabinoid that has been discussed for its
safety and efficacy in cancer treatments. For this reason, we have inquired into its use on …
safety and efficacy in cancer treatments. For this reason, we have inquired into its use on …
Quinacrine upregulates p21/p27 independent of p53 through autophagy-mediated downregulation of p62-Skp2 axis in ovarian cancer
We have previously shown that the anti-malarial compound Quinacrine (QC) inhibits ovarian
cancer (OC) growth by modulating autophagy. In the present study we extended these …
cancer (OC) growth by modulating autophagy. In the present study we extended these …
Methanolic Extract of Boswellia serrata Gum Protects the Nigral Dopaminergic Neurons from Rotenone-Induced Neurotoxicity
Boswellia serrata gum is a natural product that showed beneficial effects on
neurodegenerative diseases in recent studies. In this study, we investigated the effects of …
neurodegenerative diseases in recent studies. In this study, we investigated the effects of …