Long covid—mechanisms, risk factors, and management

H Crook, S Raza, J Nowell, M Young, P Edison - bmj, 2021 - bmj.com
Since its emergence in Wuhan, China, covid-19 has spread and had a profound effect on
the lives and health of people around the globe. As of 4 July 2021, more than 183 million …

Delirium in critical illness: clinical manifestations, outcomes, and management

JL Stollings, K Kotfis, G Chanques, BT Pun… - Intensive care …, 2021 - Springer
Delirium is the most common manifestation of brain dysfunction in critically ill patients. In the
intensive care unit (ICU), duration of delirium is independently predictive of excess death …

Effect of early mobilisation on long-term cognitive impairment in critical illness in the USA: a randomised controlled trial

BK Patel, KS Wolfe, SB Patel, KC Dugan… - The Lancet …, 2023 - thelancet.com
Background Patients who have received mechanical ventilation can have prolonged
cognitive impairment for which there is no known treatment. We aimed to establish whether …

Delirium

JE Wilson, MF Mart, C Cunningham… - Nature Reviews …, 2020 - nature.com
Delirium, a syndrome characterized by an acute change in attention, awareness and
cognition, is caused by a medical condition that cannot be better explained by a pre-existing …

Immediate and long-term consequences of COVID-19 infections for the development of neurological disease

MT Heneka, D Golenbock, E Latz, D Morgan… - Alzheimer's research & …, 2020 - Springer
Increasing evidence suggests that infection with Sars-CoV-2 causes neurological deficits in
a substantial proportion of affected patients. While these symptoms arise acutely during the …

COVID-19: ICU delirium management during SARS-CoV-2 pandemic

K Kotfis, S Williams Roberson, JE Wilson, W Dabrowski… - Critical care, 2020 - Springer
The novel coronavirus, SARS-CoV-2-causing Coronavirus Disease 19 (COVID-19),
emerged as a public health threat in December 2019 and was declared a pandemic by the …

Delirium and encephalopathy in severe COVID-19: a cohort analysis of ICU patients

J Helms, S Kremer, H Merdji, M Schenck, F Severac… - Critical care, 2020 - Springer
Abstract Background Neurotropism of SARS-CoV-2 and its neurological manifestations have
now been confirmed. We aimed at describing delirium and neurological symptoms of COVID …

Addressing the post-acute sequelae of SARS-CoV-2 infection: a multidisciplinary model of care

AM Parker, E Brigham, B Connolly… - The Lancet …, 2021 - thelancet.com
Summary As of July 31, 2021, SARS-CoV-2 had infected almost 200 million people
worldwide. The growing burden of survivorship is substantial in terms of the complexity of …

Association of delirium with long-term cognitive decline: a meta-analysis

TE Goldberg, C Chen, Y Wang, E Jung… - JAMA …, 2020 - jamanetwork.com
Importance Delirium is associated with increased hospital costs, health care complications,
and increased mortality. Long-term consequences of delirium on cognition have not been …

Cognitive impact of COVID-19: looking beyond the short term

S Miners, PG Kehoe, S Love - Alzheimer's research & therapy, 2020 - Springer
COVID-19 is primarily a respiratory disease but up to two thirds of hospitalised patients show
evidence of central nervous system (CNS) damage, predominantly ischaemic, in some …