Growth hormone—past, present and future

MB Ranke, JM Wit - Nature Reviews Endocrinology, 2018 - nature.com
Growth hormone (GH) research and its clinical application for the treatment of growth
disorders span more than a century. During the first half of the 20th century, clinical …

Diagnosis, genetics, and therapy of short stature in children: a growth hormone research society international perspective

PF Collett-Solberg, G Ambler, PF Backeljauw… - Hormone research in …, 2019 - karger.com
Abstract The Growth Hormone Research Society (GRS) convened a Workshop in March
2019 to evaluate the diagnosis and therapy of short stature in children. Forty-six …

Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours: a consensus statement

MCS Boguszewski, CL Boguszewski… - European Journal of …, 2022 - academic.oup.com
Growth hormone (GH) has been used for over 35 years, and its safety and efficacy has been
studied extensively. Experimental studies showing the permissive role of GH/insulin-like …

Hypothalamic–pituitary and growth disorders in survivors of childhood cancer: an Endocrine Society clinical practice guideline

CA Sklar, Z Antal, W Chemaitilly… - The Journal of …, 2018 - academic.oup.com
Objective To formulate clinical practice guidelines for the endocrine treatment of
hypothalamic–pituitary and growth disorders in survivors of childhood cancer. Participants …

Safety and efficacy of pediatric growth hormone therapy: results from the full KIGS cohort

M Maghnie, MB Ranke, ME Geffner… - The Journal of …, 2022 - academic.oup.com
Abstract Context The Kabi/Pfizer International Growth Database (KIGS) is a large,
international database (1987-2012) of children treated with recombinant human growth …

Advances in differential diagnosis and management of growth hormone deficiency in children

C Hage, HW Gan, A Ibba, G Patti, M Dattani… - Nature Reviews …, 2021 - nature.com
Growth hormone (GH) deficiency (GHD) in children is defined as impaired production of GH
by the pituitary gland that results in growth failure. This disease might be congenital or …

[HTML][HTML] The 2017 Korean National Growth Charts for children and adolescents: development, improvement, and prospects

JH Kim, S Yun, S Hwang, JO Shim… - Korean journal of …, 2018 - ncbi.nlm.nih.gov
Growth charts are curves or tables that facilitate the visualization of anthropometric
parameters, and are widely used as an important indicator when evaluating the growth …

Diagnosis and testing for growth hormone deficiency across the ages: a global view of the accuracy, caveats, and cut-offs for diagnosis

KCJ Yuen, G Johannsson, KKY Ho… - Endocrine …, 2023 - ec.bioscientifica.com
Growth hormone deficiency (GHD) is a clinical syndrome that can manifest either as isolated
or associated with additional pituitary hormone deficiencies. Although diminished height …

Materials-based nanotherapeutics for injured and diseased bone

CS Lee, RK Singh, HS Hwang, NH Lee… - Progress in Materials …, 2023 - Elsevier
Severe injuries and diseases of bone tissue caused by congenital disorder, extrinsic trauma,
infection, and osteosarcoma resection face significant challenges for complete recovery. The …

[HTML][HTML] Impact of short stature on quality of life: a systematic literature review

P Backeljauw, M Cappa, W Kiess, L Law… - Growth Hormone & IGF …, 2021 - Elsevier
Objective We sought to obtain a better understanding of the burden of short stature using a
systematic literature review. Methods Studies of the burden of short stature, of any cause in …