Our populations are aging. Some experts predict that 30% of hospital beds will soon be
occupied by osteoporosis patients. Statistics show that 20% of patients suffering from an …

Immunoassay as a rapid and convenient method for detecting a variety of targets has
attracted tremendous interest with its high specificity and sensitivity. Among the commonly …

Inorganic polyphosphate (polyP) is the polymer of orthophosphate and can be found in all
living organisms. For polyP characterization, one or more of six parameters are of interest …

Calcified cartilage regeneration plays an important role in successful osteochondral repair,
since it provides a biological and mechanical transition from the unmineralized cartilage at …

Nanoceria with phosphatase-like behavior shows its great potential for many important
biological applications through a catalytic dephosphorylation process. Herein, we …

Given heavy metals pose huge threats to ecological system and human health, it is
significant to monitor them. With the favorable feature of catalytic signal amplification, redox …

The endoskeleton of elasmobranchs (sharks and rays) is comprised largely of
unmineralized cartilage, differing fundamentally from the bony skeletons of other …

In human bone, amorphous calcium carbonate (ACC) is formed as a precursor of the
crystalline carbonated apatite/hydroxyapatite (HA). Here we describe that the metastable …

Polyphosphate (polyP) is an abundant and physiologically important biomolecule for
virtually any living cell. Therefore, determination of changes in cellular content of polyP is …

Patients with bone and cartilage defects due to infection, tumors, and trauma are quite
common. Repairing bone and cartilage defects is thus a major problem for clinicians …