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T‐cell exhaustion in HIV infection
The T‐cell response is central in the adaptive immune‐mediated elimination of pathogen‐
infected and/or cancer cells. This activated T‐cell response can inflict an overwhelming …
infected and/or cancer cells. This activated T‐cell response can inflict an overwhelming …
Incomplete immune reconstitution in HIV/AIDS patients on antiretroviral therapy: Challenges of immunological non-responders
The morbidity and mortality of HIV type-1 (HIV-1)-related diseases were dramatically
diminished by the grounds of the introduction of potent antiretroviral therapy, which induces …
diminished by the grounds of the introduction of potent antiretroviral therapy, which induces …
Markers of immune activation and inflammation in individuals with postacute sequelae of severe acute respiratory syndrome coronavirus 2 infection
Background The biological processes associated with postacute sequelae of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) are unknown. Methods …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) are unknown. Methods …
[HTML][HTML] Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study
Background The risk of severe COVID-19 if an individual becomes infected is known to be
higher in older individuals and those with underlying health conditions. Understanding the …
higher in older individuals and those with underlying health conditions. Understanding the …
[HTML][HTML] Utilization of immunological ratios in HIV: Implications for monitoring and therapeutic strategies
Human immunodeficiency virus (HIV) infection remains a significant global health concern,
necessitating ongoing research and innovation in the quest for improved disease …
necessitating ongoing research and innovation in the quest for improved disease …
[PDF][PDF] Implications of CD4/CD8 ratios in Human Immunodeficiency Virus infections
Abstract Human Immunodeficiency Virus (HIV) is a major Public Health burden to the world
despite all efforts to eradicate the menace. HIV infection is characterized by profound CD4 T …
despite all efforts to eradicate the menace. HIV infection is characterized by profound CD4 T …
Humoral and cellular immune response elicited by mRNA vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in people living with …
Abstract Background Data on SARS-CoV-2 vaccine immunogenicity in PLWH are currently
limited. Aim of the study was to investigate immunogenicity according to current CD4 T-cell …
limited. Aim of the study was to investigate immunogenicity according to current CD4 T-cell …
[HTML][HTML] Classical swine fever virus: the past, present and future
Classical swine fever (CSF) is among the most relevant viral epizootic diseases of swine.
Due to its severe economic impact, CSF is notifiable to the world organisation for animal …
Due to its severe economic impact, CSF is notifiable to the world organisation for animal …
Imbalance in the game of T cells: What can the CD4/CD8 T-cell ratio tell us about HIV and health?
Antiretroviral treatment (ART) has transformed human immunodeficiency virus (HIV) from a
deadly disease to a chronic illness that potentially has little effect on life expectancy. Modern …
deadly disease to a chronic illness that potentially has little effect on life expectancy. Modern …
HIV infection
More than 75 million people worldwide have been infected with human immunodeficiency
virus (HIV), and there are now approximately 37 million individuals living with the infection …
virus (HIV), and there are now approximately 37 million individuals living with the infection …