Schizophrenia is a widespread psychiatric disorder that affects 0.5–1.0% of the world's
population and induces significant, long-term disability that exacts high personal and …

Every common psychiatric syndrome is genetically, neurobiologically and clinically
heterogeneous. This heterogeneity may reflect the dimensional variability of a single illness …

Importance Between-individual variability in brain structure is determined by gene-
environment interactions, possibly reflecting differential sensitivity to environmental and …

Background The profile of cortical neuroanatomical abnormalities in schizophrenia is not
fully understood, despite hundreds of published structural brain imaging studies. This study …

Background: The COVID-19 pandemic has attracted the attention of researchers and
clinicians whom have provided evidence about risk factors and clinical outcomes. Research …

Technical developments and improved access to neuroimaging techniques have brought us
closer to understanding the neuropathological origins of schizophrenia. Using data-driven …

Using machine learning, we recently decomposed the neuroanatomical heterogeneity of
established schizophrenia to discover two volumetric subgroups—a 'lower brain …

Disease heterogeneity is a significant obstacle to understanding pathological processes and
delivering precision diagnostics and treatment. Clustering methods have gained popularity …

Objectives The profiles of cortical abnormalities in schizophrenia and bipolar disorder, and
how far they resemble each other, have only been studied to a limited extent. The aim of this …

The diagnosis of schizophrenia is thought to embrace several distinct subgroups. The
manifold entities in a single clinical patient group increase the variance of biological …