[HTML][HTML] An overview of vaccine adjuvants: current evidence and future perspectives

A Facciolà, G Visalli, A Laganà, A Di Pietro - Vaccines, 2022 - mdpi.com
Vaccinations are one of the most important preventive tools against infectious diseases.
Over time, many different types of vaccines have been developed concerning the antigen …

Amino assets: how amino acids support immunity

B Kelly, EL Pearce - Cell metabolism, 2020 - cell.com
Amino acids are fundamental building blocks supporting life. Their role in protein synthesis
is well defined, but they contribute to a host of other intracellular metabolic pathways …

[HTML][HTML] Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled …

MS Datoo, MH Natama, A Somé, O Traoré, T Rouamba… - The Lancet, 2021 - thelancet.com
Background Stalled progress in controlling Plasmodium falciparum malaria highlights the
need for an effective and deployable vaccine. RTS, S/AS01, the most effective malaria …

RTS, S/AS01 vaccine (Mosquirix™): an overview

MB Laurens - Human vaccines & immunotherapeutics, 2020 - Taylor & Francis
Malaria is an illness caused by Plasmodium parasites transmitted to humans by infected
mosquitoes. Of the five species that infect humans, P. falciparum exacts the highest toll in …

Malaria vaccines: the 60-year journey of hope and final success—lessons learned and future prospects

AA El-Moamly, MA El-Sweify - Tropical Medicine and Health, 2023 - Springer
Background The world has made great strides towards beating malaria, although about half
of the world population is still exposed to the risk of contracting malaria. Develo** an …

Malaria vaccines: recent advances and new horizons

SJ Draper, BK Sack, CR King, CM Nielsen, JC Rayner… - Cell host & …, 2018 - cell.com
The development of highly effective and durable vaccines against the human malaria
parasites Plasmodium falciparum and P. vivax remains a key priority. Decades of endeavor …

Malaria vaccines: progress to date

DI Stanisic, MF Good - BioDrugs, 2023 - Springer
Malaria is a mosquito-borne disease caused by protozoan parasites of the genus
Plasmodium. Despite significant declines in malaria-attributable morbidity and mortality over …

T cell-mediated immunity to malaria

SP Kurup, NS Butler, JT Harty - Nature Reviews Immunology, 2019 - nature.com
Immunity to malaria has been linked to the availability and function of helper CD4+ T cells,
cytotoxic CD8+ T cells and γδ T cells that can respond to both the asymptomatic liver stage …

Cytokines and chemokines in cerebral malaria pathogenesis

J Dunst, F Kamena, K Matuschewski - Frontiers in cellular and …, 2017 - frontiersin.org
Cerebral malaria is among the major causes of malaria-associated mortality and effective
adjunctive therapeutic strategies are currently lacking. Central pathophysiological processes …

Vaccines and monoclonal antibodies: new tools for malaria control

K Miura, Y Flores-Garcia, CA Long… - Clinical Microbiology …, 2024 - journals.asm.org
Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …