Challenges and applications of artificial intelligence in infectious diseases and antimicrobial resistance

A Cesaro, SC Hoffman, P Das… - npj Antimicrobials and …, 2025 - nature.com
Artificial intelligence (AI) has transformed infectious disease control, enhancing rapid
diagnosis and antibiotic discovery. While conventional tests delay diagnosis, AI-driven …

Artificial intelligence in drug development

K Zhang, X Yang, Y Wang, Y Yu, N Huang, G Li, X Li… - Nature Medicine, 2025 - nature.com
Drug development is a complex and time-consuming endeavor that traditionally relies on the
experience of drug developers and trial-and-error experimentation. The advent of artificial …

Institutional efforts to help academic researchers implement generative AI in research

J Liu, HV Jagadish - Harvard Data Science Review, 2024 - hdsr.mitpress.mit.edu
The scale and speed of the generative AI (artificial intelligence) revolution, while offering
unprecedented opportunities to advance science, is also challenging the traditional …

[HTML][HTML] IUPHAR review–Data-driven computational drug repurposing approaches for opioid use disorder

Z Gao, P Ding, R Xu - Pharmacological Research, 2024 - Elsevier
Abstract Opioid Use Disorder (OUD) is a chronic and relapsing condition characterized by
the misuse of opioid drugs, causing significant morbidity and mortality in the United States …

The Promises and Perils of Foundation Models in Dermatology

H Gui, JA Omiye, CT Chang, R Daneshjou - Journal of Investigative …, 2024 - Elsevier
Foundation models (FM), which are large-scale artificial intelligence (AI) models that can
complete a range of tasks, represent a paradigm shift in AI. These versatile models …

How deep learning in antiviral molecular profiling identified anti-SARS-CoV-2 inhibitors

M Ali, IH Park, J Kim, G Kim, J Oh, JS You, J Kim… - Biomedicines, 2023 - mdpi.com
The integration of artificial intelligence (AI) into drug discovery has markedly advanced the
search for effective therapeutics. In our study, we employed a comprehensive computational …

Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies

N Altincekic, N Jores, F Löhr, C Richter… - ACS Chemical …, 2024 - ACS Publications
The main protease Mpro, nsp5, of SARS-CoV-2 (SCoV2) is one of its most attractive drug
targets. Here, we report primary screening data using nuclear magnetic resonance …