Iron homeostasis and ferroptosis in human diseases: mechanisms and therapeutic prospects

Q Ru, Y Li, L Chen, Y Wu, J Min, F Wang - Signal transduction and …, 2024 - nature.com
Iron, an essential mineral in the body, is involved in numerous physiological processes,
making the maintenance of iron homeostasis crucial for overall health. Both iron overload …

The impact of oxidative stress-induced mitochondrial dysfunction on diabetic microvascular complications

Z Zhang, Q Huang, D Zhao, F Lian, X Li… - Frontiers in …, 2023 - frontiersin.org
Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycaemia,
with absolute insulin deficiency or insulin resistance as the main cause, and causes damage …

Guidelines on interventions to enhance healing of foot ulcers in people with diabetes (IWGDF 2023 update)

P Chen, NC Vilorio, K Dhatariya… - Diabetes/metabolism …, 2024 - Wiley Online Library
Aims Principles of wound management, including debridement, wound bed preparation, and
newer technologies involving alternation of wound physiology to facilitate healing, are of …

[HTML][HTML] Ferroptosis and ferritinophagy in diabetes complications

J He, Z Li, P **a, A Shi, X FuChen, J Zhang, P Yu - Molecular Metabolism, 2022 - Elsevier
Background With long-term metabolic malfunction, diabetes can cause serious damage to
whole-body tissue and organs, resulting in a variety of complications. Therefore, it is …

Insights into the mechanisms of diabetic wounds: pathophysiology, molecular targets, and treatment strategies through conventional and alternative therapies

JP Yadav, AK Singh, M Grishina, P Pathak… - …, 2024 - Springer
Diabetes mellitus is a prevalent cause of mortality worldwide and can lead to several
secondary issues, including DWs, which are caused by hyperglycemia, diabetic neuropathy …

Effectiveness of interventions to enhance healing of chronic foot ulcers in diabetes: a systematic review

P Chen, NC Vilorio, K Dhatariya… - Diabetes/Metabolism …, 2024 - Wiley Online Library
Background It is critical that interventions used to enhance the healing of chronic foot ulcers
in diabetes are backed by high‐quality evidence and cost‐effectiveness. In previous years …

Vitamin C supplementation for diabetes management: A comprehensive narrative review

SA Mason, L Parker, P van der Pligt… - Free Radical Biology and …, 2023 - Elsevier
Growing evidence suggests that vitamin C supplementation may be an effective adjunct
therapy in the management of people with diabetes. This paper critically reviews the current …

[HTML][HTML] A systematic review on the role of vitamin C in tissue healing

N Bechara, VM Flood, JE Gunton - Antioxidants, 2022 - mdpi.com
Vitamin C is an essential nutrient for humans and animals which are unable to synthesise it
themselves. Vitamin C is important for tissue regeneration due to the role it plays in collagen …

Innovative functional biomaterials as therapeutic wound dressings for chronic diabetic foot ulcers

J Da Silva, EC Leal, E Carvalho, EA Silva - International Journal of …, 2023 - mdpi.com
The imbalance of local and systemic factors in individuals with diabetes mellitus (DM)
delays, or even interrupts, the highly complex and dynamic process of wound healing …

Therapeutic potential of palm oil vitamin E-derived tocotrienols in inflammation and chronic diseases: Evidence from preclinical and clinical studies

Z Zainal, H Khaza'ai, AK Radhakrishnan… - Food Research …, 2022 - Elsevier
Palm oil is rich in tocotrienols (T3s), a type of vitamin E that has garnered considerable
research interest as it exhibits anti-inflammatory as well as antioxidant characteristics that …