Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
[HTML][HTML] Desmoplastic small round cell tumor: a review of main molecular abnormalities and emerging therapy
Simple Summary Desmoplastic small round cell tumor is a rare neoplasm with extremely
aggressive behavior. Despite the multimodal treatment for newly diagnosed patients with …
aggressive behavior. Despite the multimodal treatment for newly diagnosed patients with …
Integrative genomic and transcriptomic analysis of leiomyosarcoma
Leiomyosarcoma (LMS) is an aggressive mesenchymal malignancy with few therapeutic
options. The mechanisms underlying LMS development, including clinically actionable …
options. The mechanisms underlying LMS development, including clinically actionable …
An update on emerging drugs in osteosarcoma: towards tailored therapies?
CM Hattinger, MP Patrizio, F Magagnoli… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Current treatment of conventional and non-conventional high-grade
osteosarcoma (HGOS) is based on the surgical removal of primary tumor and, when …
osteosarcoma (HGOS) is based on the surgical removal of primary tumor and, when …
Patient-specific sarcoma organoids for personalized translational research: unification of the operating room with rare cancer research and clinical implications
Introduction Sarcoma clinical outcomes have been stagnant for decades due to
heterogeneity of primaries, lack of comprehensive preclinical models, and rarity of disease …
heterogeneity of primaries, lack of comprehensive preclinical models, and rarity of disease …
Reading ADP-ribosylation signaling using chemical biology and interaction proteomics
ADP-ribose (ADPr) readers are essential components of ADP-ribosylation signaling, which
regulates genome maintenance and immunity. The identification and discrimination …
regulates genome maintenance and immunity. The identification and discrimination …
Trabectedin and olaparib in patients with advanced and non-resectable bone and soft-tissue sarcomas (TOMAS): an open-label, phase 1b study from the Italian …
G Grignani, L D'Ambrosio, Y Pignochino… - The Lancet …, 2018 - thelancet.com
Background Trabectedin is an alkylating drug with a unique mechanism of action causing
single-strand and double-strand DNA breaks that activate DNA damage-response …
single-strand and double-strand DNA breaks that activate DNA damage-response …
Analysis of mutational signatures with yet another package for signature analysis
Different mutational processes leave characteristic patterns of somatic mutations in the
genome that can be identified as mutational signatures. Determining the contributions of …
genome that can be identified as mutational signatures. Determining the contributions of …
[HTML][HTML] Identification of differentially expressed genes between original breast cancer and xenograft using machine learning algorithms
Breast cancer is one of the most common malignancies in women. Patient-derived tumor
xenograft (PDX) model is a cutting-edge approach for drug research on breast cancer …
xenograft (PDX) model is a cutting-edge approach for drug research on breast cancer …
Bone sarcomas in the immunotherapy era
Bone sarcomas are primary bone tumours found mainly in children and adolescents, as
osteosarcoma and Ewing's sarcoma, and in adults in their 40s as chondrosarcoma. The last …
osteosarcoma and Ewing's sarcoma, and in adults in their 40s as chondrosarcoma. The last …
[HTML][HTML] Targeted and immuno-based therapies in sarcoma: mechanisms and advances in clinical trials
Sarcomas represent a distinct group of rare malignant tumors with high heterogeneity.
Limited options with clinical efficacy for the metastatic or local advanced sarcoma existed …
Limited options with clinical efficacy for the metastatic or local advanced sarcoma existed …