Recent applications of analytical quality-by-design methodology for chromatographic analysis: A review

DT Xuan, HMT Nguyen, VD Hoang - Chemometrics and Intelligent …, 2024 - Elsevier
ABSTRACT Analytical Quality-by-Design (AQbD) represents a systematic methodology for
method development. The pharmaceutical and biopharmaceutical industries have …

Eco-friendly and green chromatographic method for the simultaneous determination of chlorocresol and betamethasone dipropionate in topical formulations using Box …

SK Muchakayala, NK Katari, T Dongala… - Journal of the Iranian …, 2022 - Springer
Betamethasone dipropionate topical formulations are using to treat anti-inflammatory skin
diseases such as dermatitis, eczema, and psoriasis. The current research study confers the …

A simple and rapid HPLC method for determination of parabens and their degradation products in pharmaceutical dosage forms

LNR Katakam, SK Ettaboina… - Biomedical …, 2021 - Wiley Online Library
A stability‐indicating HPLC method was developed for the simultaneous determination of
paraben mixture and its degradation products in effervescent potassium chloride tablets …

[HTML][HTML] Quality-by-design-driven nanostructured lipid Scaffold of Apixaban: optimization, characterization, and pharmacokinetic evaluation

K Patil, N Gujarathi, C Sharma, S Ojha, S Goyal… - Pharmaceutics, 2024 - mdpi.com
Apixaban, an anticoagulant, is limited in its efficacy due to poor solubility, low bioavailability,
and extensive metabolism. This study investigates the application of nanostructured lipid …

Green fitted second derivative synchronous spectrofluorometric method for simultaneous determination of remdesivir and apixaban at Nano gram scale in the spiked …

AS Batubara, AH Abdelazim, M Gamal… - … Acta Part A: Molecular …, 2023 - Elsevier
Remdesivir and apixaban have been included in the treatment guidelines of several
countries for severe COVID-19 infections. To date, no analytical method has been …

Quality by design with design of experiments approach for development of a stability‐indicating LC method for enzalutamide and its impurities in soft gel dosage …

LNR Katakam, T Dongala… - Biomedical …, 2021 - Wiley Online Library
A novel ultra‐performance liquid chromatographic (UPLC) method has been developed and
approved for the quantitative determination of enzalutamide (ENZ) and its impurities in drug …

Development and validation of liquid chromatography method for determination of Ibrutinib in finished dosage forms using quality by design approach

N Konduru, R Gundla, T Dongala… - Separation …, 2022 - Wiley Online Library
A simple, precise, linear, robust, accurate, and stability‐indicating liquid chromatography
method was developed and validated to determine Ibrutinib in finished solid dosage forms …

Stability‐indicating ultra performance liquid chromatography method development and validation for simultaneous estimation of metformin, linagliptin, and …

KR Vankalapati, P Alegete… - Biomedical …, 2021 - Wiley Online Library
A rapid stability‐indicating reversed phase‐ultrapure liquid chromatography (RP‐UPLC)
was developed and validated for the estimation of metformin (MET), linagliptin (LIN), and …

Quality by design (QbD) based method for estimation of xanthohumol in bulk and solid lipid nanoparticles and validation

V Harish, WH Almalki, A Alshehri, A Alzahrani… - Molecules, 2023 - mdpi.com
The analytical quality by design (AQbD) approach is utilized for develo** and validating
the simple, sensitive, cost-effective reverse-phase high performance liquid chromatographic …

A simple high‐performance liquid chromatography method development for carbidopa and levodopa impurities: Evaluation of risk assessment before method …

VB Subramanian, N Konduru, NK Katari… - Separation …, 2020 - Wiley Online Library
The current study is to develop a simple high‐performance liquid chromatography method
for Carbidopa and Levodopa impurities' simultaneous determination with the combination of …