Epidemiological sex differences in anxiety disorders and major depression are well
characterized. Yet the circuits and mechanisms that contribute to these differences are …

Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are
associated with systemic inflammation. Recent studies have reported stress-induced …

In humans, traumatic social experiences can contribute to psychiatric disorders. It is
suggested that social trauma impairs brain reward function such that social behaviour is no …

The neurodevelopmental and dopamine hypotheses are leading theories of the
pathoetiology of schizophrenia, but they were developed in isolation. However, since they …

Stress is a primary risk factor for several neuropsychiatric disorders. Evidence from
preclinical models and clinical studies of depression have revealed an array of structural …

Prevalence, symptoms, and treatment of depression suggest that major depressive
disorders (MDD) present sex differences. Social stress-induced neurovascular pathology is …

Studies suggest that heightened peripheral inflammation contributes to the pathogenesis of
major depressive disorder. We investigated the effect of chronic social defeat stress, a …

Depression represents a global mental health concern, and disproportionally affects women
as they are twice more likely to be diagnosed than men. In this review, we provide a …

Over the last five decades, a large body of evidence has accrued for structural and metabolic
brain alterations in schizophrenia. Here we provide an overview of these findings, focusing …

Major depressive disorder (MDD) is a leading cause of disease burden worldwide. While the
incidence, symptoms and treatment of MDD all point toward major sex differences, the …