The progress of small molecules against cannabinoid 2 receptor (CB2R)

Q Zhang, Y Zhao, J Wu, W Zhong, W Huang, Y Pan - Bioorganic Chemistry, 2024 - Elsevier
The two subtypes of cannabinoid receptors (CBR), namely CB 1 R and CB 2 R, belong to
the G protein-coupled receptor (GPCR) superfamily and are confirmed as potential …

[HTML][HTML] Comparison of Agonist Activity between CB1 and CB2 Receptors with Orthosteric Site Mutations

CA Brust, MA Swanson, CI Tsoutsouvas, ST Dimova… - Receptors, 2024 - mdpi.com
Human endocannabinoid signaling is primarily mediated by the cannabinoid receptors, CB1
and CB2, which are G protein-coupled receptors (GPCRs). These receptors have been …

Bioactive Constituents Interactions with 5-HT2C and PDE-5 Receptors in Herbal Drug Mixtures used in the treatment Of Premature Ejaculation sold in Anambra State …

CI Aghanwa, UE Ekpunobi… - Medicinal and Medical …, 2024 - medmedchem.com
This study sought to evaluate the efficacy of bioactive compounds in herbal remedies
available in Awka, Anambra State, for addressing premature ejaculation via interactions with …

[CITÁCIA][C] Machine learning and deep learning based scoring functions in deciphering ligand-receptor binding: An application in drug design for GPCRs

T Niu, NX Wang, J Wang - 2024 - Elsevier