[HTML][HTML] An overview into polyethylene terephthalate (PET) hydrolases and efforts in tailoring enzymes for improved plastic degradation

NFS Khairul Anuar, F Huyop, G Ur-Rehman… - International Journal of …, 2022 - mdpi.com
Plastic or microplastic pollution is a global threat affecting ecosystems, with the current
generation reaching as much as 400 metric tons per/year. Soil ecosystems comprising …

Hormone-sensitive lipase: sixty years later

E Recazens, E Mouisel, D Langin - Progress in lipid research, 2021 - Elsevier
Hormone-sensitive lipase (HSL) was initially characterized as the hormonally regulated
neutral lipase activity responsible for the breakdown of triacylglycerols into fatty acids in …

Bacterial lactonases ZenA with noncanonical structural features hydrolyze the mycotoxin zearalenone

S Fruhauf, D Puhringer, M Thamhesl, P Fajtl… - ACS …, 2024 - ACS Publications
Zearalenone (ZEN) is a mycoestrogenic polyketide produced by Fusarium graminearum and
other phytopathogenic members of the genus Fusarium. Contamination of cereals with ZEN …

Molecular insights into the catalytic mechanism of a phthalate ester hydrolase

N Wang, N Zhang, ML Sun, Y Sun, QY Dong… - Journal of Hazardous …, 2024 - Elsevier
Phthalate esters (PAEs) are emerging hazardous and toxic chemicals that are extensively
used as plasticizers or additives. Diethyl phthalate (DEP) and dimethyl phthalate (DMP), two …

Metagenomic mining for thermostable esterolytic enzymes uncovers a new family of bacterial esterases

D Zarafeta, D Moschidi, E Ladoukakis, S Gavrilov… - Scientific reports, 2016 - nature.com
Biocatalysts exerting activity against ester bonds have a broad range of applications in
modern biotechnology. Here, we have identified a new esterolytic enzyme by screening a …

Carboxylic ester hydrolases from hyperthermophiles

M Levisson, J van der Oost, SWM Kengen - Extremophiles, 2009 - Springer
Carboxylic ester hydrolyzing enzymes constitute a large group of enzymes that are able to
catalyze the hydrolysis, synthesis or transesterification of an ester bond. They can be found …

Interdomain hydrophobic interactions modulate the thermostability of microbial esterases from the hormone-sensitive lipase family

PY Li, XL Chen, P Ji, CY Li, P Wang, Y Zhang… - Journal of Biological …, 2015 - jbc.org
Microbial hormone-sensitive lipases (HSLs) contain a CAP domain and a catalytic domain.
However, it remains unclear how the CAP domain interacts with the catalytic domain to …

Functional and structural studies of a novel cold-adapted esterase from an Arctic intertidal metagenomic library

J Fu, HKS Leiros, D de Pascale, KA Johnson… - Applied microbiology …, 2013 - Springer
A novel cold-adapted lipolytic enzyme gene, est97, was identified from a high Arctic
intertidal zone sediment metagenomic library. The deduced amino acid sequence of Est97 …

The metagenome-derived enzymes LipS and LipT increase the diversity of known lipases

J Chow, F Kovacic, Y Dall Antonia, U Krauss, F Fersini… - PloS one, 2012 - journals.plos.org
Triacylglycerol lipases (EC 3.1. 1.3) catalyze both hydrolysis and synthesis reactions with a
broad spectrum of substrates rendering them especially suitable for many biotechnological …

Structural basis for dimerization and catalysis of a novel esterase from the GTSAG motif subfamily of the bacterial hormone-sensitive lipase family

PY Li, P Ji, CY Li, Y Zhang, GL Wang, XY Zhang… - Journal of Biological …, 2014 - jbc.org
Hormone-sensitive lipases (HSLs) are widely distributed in microorganisms, plants, and
animals. Microbial HSLs are classified into two subfamilies, an unnamed new subfamily and …