[HTML][HTML] Mechanisms and biotechnological applications of transcription factors

H He, M Yang, S Li, G Zhang, Z Ding, L Zhang… - Synthetic and systems …, 2023‏ - Elsevier
Transcription factors play an indispensable role in maintaining cellular viability and finely
regulating complex internal metabolic networks. These crucial bioactive functions rely on …

Advances in promoter engineering: novel applications and predefined transcriptional control

AP Cazier, J Blazeck - Biotechnology Journal, 2021‏ - Wiley Online Library
Synthetic biology continues to progress by relying on more robust tools for transcriptional
control, of which promoters are the most fundamental component. Numerous studies have …

[كتاب][B] Current Developments in Biotechnology and Bioengineering: Designer Microbial Cell Factories: Metabolic Engineering and Applications

S Joshi, A Pandey, R Sirohi, SH Park - 2022‏ - books.google.com
Designer Microbial Cell Factories: Metabolic Engineering and Applications, the latest
release in the Current Developments in Biotechnology and Bioengineering series, provides …

[HTML][HTML] Merging automation and fundamental discovery into the design–build–test–learn cycle of nontraditional microbes

N Gurdo, DC Volke, PI Nikel - Trends in Biotechnology, 2022‏ - cell.com
Major advances toward a bio-based industry enabled cost-efficient bioproduction of multiple
chemicals, yet successful industrial processes are relatively scarce and limited to the use of …

[HTML][HTML] Manipulating gene expression levels in mammalian cell factories: An outline of synthetic molecular toolboxes to achieve multiplexed control

P Eisenhut, N Marx, G Borsi, M Papež, C Ruggeri… - New …, 2024‏ - Elsevier
Mammalian cells have developed dedicated molecular mechanisms to tightly control
expression levels of their genes where the specific transcriptomic signature across all genes …

High-throughput screening for efficient microbial biotechnology

A Sarnaik, A Liu, D Nielsen, AM Varman - Current Opinion in …, 2020‏ - Elsevier
Highlights•High-throughput screening (HTS) facilitates selection of the best performing
strain.•Biosensor-enabled HTS obviates the need for sophisticated analytical …

Vibrio sp. dhg as a platform for the biorefinery of brown macroalgae

HG Lim, DH Kwak, S Park, S Woo, JS Yang… - Nature …, 2019‏ - nature.com
Although brown macroalgae holds potential as an alternative feedstock, its utilization by
conventional microbial platforms has been limited due to the inability to metabolize one of …

Fundamentals and exceptions of the LysR-type transcriptional regulators

W Demeester, B De Paepe, M De Mey - ACS Synthetic Biology, 2024‏ - ACS Publications
LysR-type transcriptional regulators (LTTRs) are emerging as a promising group of
macromolecules for the field of biosensors. As the largest family of bacterial transcription …

Multilayer genetic circuits for dynamic regulation of metabolic pathways

S Cui, X Lv, X Xu, T Chen, H Zhang, Y Liu… - ACS Synthetic …, 2021‏ - ACS Publications
The dynamic regulation of metabolic pathways is based on changes in external signals and
endogenous changes in gene expression levels and has extensive applications in the field …

Genetic circuit-assisted smart microbial engineering

C Gao, P Xu, C Ye, X Chen, L Liu - Trends in microbiology, 2019‏ - cell.com
Rapid advances in DNA synthesis, genetic manipulation, and biosensors have greatly
improved the ability to engineer microorganisms with complex functions. By accurately …