Type III secretion in Chlamydia
EA Rucks - Microbiology and Molecular Biology Reviews, 2023 - Am Soc Microbiol
Type III secretion systems (T3SSs) are utilized by Gram-negative pathogens to enhance
their pathogenesis. This secretion system is associated with the delivery of effectors through …
their pathogenesis. This secretion system is associated with the delivery of effectors through …
Cell-free co-translational approaches for producing mammalian receptors: expanding the cell-free expression toolbox using nanolipoproteins
Membranes proteins make up more than 60% of current drug targets and account for
approximately 30% or more of the cellular proteome. Access to this important class of …
approximately 30% or more of the cellular proteome. Access to this important class of …
Cell-free production of a functional oligomeric form of a Chlamydia major outer-membrane protein (MOMP) for vaccine development
Chlamydia is a prevalent sexually transmitted disease that infects more than 100 million
people worldwide. Although most individuals infected with Chlamydia trachomatis are …
people worldwide. Although most individuals infected with Chlamydia trachomatis are …
Delivering the pain: an overview of the type III secretion system with special consideration for aquatic pathogens
H Rahmatelahi, M El-Matbouli… - Veterinary …, 2021 - Springer
Gram-negative bacteria are known to subvert eukaryotic cell physiological mechanisms
using a wide array of virulence factors, among which the type three-secretion system (T3SS) …
using a wide array of virulence factors, among which the type three-secretion system (T3SS) …
Cationic HDL mimetics enhance in vivo delivery of self-replicating mRNA
In vivo delivery of large RNA molecules has significant implications for novel gene therapy,
biologics delivery, and vaccine applications. We have developed cationic nanolipoprotein …
biologics delivery, and vaccine applications. We have developed cationic nanolipoprotein …
Macrophage innate immune responses delineate between defective translocon assemblies produced by Yersinia pseudotuberculosis YopD mutants
Translocon pores formed in the eukaryotic cell membrane by a type III secretion system
facilitate the translocation of immune-modulatory effector proteins into the host cell interior …
facilitate the translocation of immune-modulatory effector proteins into the host cell interior …
Single-molecule fluorescence detection of the epidermal growth factor receptor in membrane discs
The epidermal growth factor receptor (EGFR) is critical to normal cellular signaling
pathways. Moreover, it has been implicated in a range of pathologies, including cancer. As a …
pathways. Moreover, it has been implicated in a range of pathologies, including cancer. As a …
Bimolecular fluorescence complementation assay to explore protein-protein interactions of the Yersinia virulence factor YopM
Yersinia outer protein M (YopM) is one of the effector proteins and essential for virulence.
YopM is delivered by the Yersinia type III secretion system (T3SS) into the host cell, where it …
YopM is delivered by the Yersinia type III secretion system (T3SS) into the host cell, where it …
Methods and systems for producing nanolipoprotein particles
2018-12-17 Assigned to LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
reassignment LAWRENCE LIVERMORE NATIONAL SECURITY, LLC ASSIGNMENT OF …
reassignment LAWRENCE LIVERMORE NATIONAL SECURITY, LLC ASSIGNMENT OF …
Cell-free scaled production and adjuvant addition to a recombinant major outer membrane protein from chlamydia muridarum for vaccine development
Subunit vaccines offer advantages over more traditional inactivated or attenuated whole-cell-
derived vaccines in safety, stability, and standard manufacturing. To achieve an effective …
derived vaccines in safety, stability, and standard manufacturing. To achieve an effective …