Revisiting immunotherapy: a focus on prostate cancer

HR Cha, JH Lee, S Ponnazhagan - Cancer research, 2020‏ - aacrjournals.org
Therapeutic interventions to harness the immune system against tumor cells have provided
mixed results in the past for several solid tumors and hematologic malignancies. However …

Obesity and main urologic cancers: Current systematic evidence, novel biological mechanisms, perspectives and challenges

G Papavasileiou, D Tsilingiris, N Spyrou… - Seminars in Cancer …, 2023‏ - Elsevier
Urologic cancers (UC) account for 13.1% of all new cancer cases and 7.9% of all cancer-
related deaths. A growing body of evidence has indicated a potential causal link between …

Thermosensitive hydrogel with emodin-loaded triple-targeted nanoparticles for a rectal drug delivery system in the treatment of chronic non-bacterial prostatitis

Y Ye, W Zhong, R Luo, H Wen, Z Ma, S Qi… - Journal of …, 2024‏ - Springer
Background The complex etiology and pathogenesis underlying Chronic Non-Bacterial
Prostatitis (CNP), coupled with the existence of a Blood Prostate Barrier (BPB), contribute to …

[HTML][HTML] Impact of sexual activity on the risk of male genital tumors: a systematic review of the literature

F Crocetto, D Arcaniolo, L Napolitano… - International journal of …, 2021‏ - mdpi.com
Most cancers are related to lifestyle and environmental risk factors, including smoking,
alcohol consumption, dietary habits, and environment (occupational exposures). A growing …

Exposure to an environmentally relevant phthalate mixture during prostate development induces microRNA upregulation and transcriptome modulation in rats

WR Scarano, A Bedrat, LG Alonso-Costa… - Toxicological …, 2019‏ - academic.oup.com
Environmental exposure to phthalates during intrauterine development might increase
susceptibility to neoplasms in reproductive organs such as the prostate. Although studies …

Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer

JO Mori, I Elhussin, WN Brennen, MK Graham… - Nature Reviews …, 2024‏ - nature.com
The stromal component of the tumour microenvironment in primary and metastatic prostate
cancer can influence and promote disease progression. Within the prostatic stroma …

Advances in research on the interaction between inflammation and cancer

XD Song, YN Wang, A Zhang… - Journal of International …, 2020‏ - journals.sagepub.com
Inflammation is the body's response to cell damage. Cancer is a general term that describes
all malignant tumours. There are no confirmed data on cancer-related inflammation, but …

Association Between Pretreatment Blood 25-Hydroxyvitamin D Level and Survival Outcomes in Patients With Clinically Localized Prostate Cancer: An Updated Meta …

F Cui, Y Qiu, W Xu, C Zou, Y Fan - Nutrition and Cancer, 2024‏ - Taylor & Francis
Studies on the prognostic value of the blood 25-hydroxyvitamin D level have yielded
controversial results in prostate cancer (PCa) patients. This updated meta-analysis aimed to …

Notoginsenoside R1 induces oxidative stress and modulates LPS induced immune microenvironment of nasopharyngeal carcinoma

S Li, G Pi, Y Zeng, C Ruan, X He, X **ong… - International …, 2022‏ - Elsevier
Background Nasopharyngeal carcinoma (NPC) is a malignant tumor with high incidence.
Notoginsenoside R1 (NGR1) is the main active compound of total Panax notoginseng …

Bacterial signatures and their inflammatory potentials associated with prostate cancer

H Brüggemann, MA Al‐Zeer - Apmis, 2020‏ - Wiley Online Library
Chronic inflammation can create a microenvironment that can contribute to the formation of
prostate pathologies. Far less well understood is the origin of inflammation in the prostate …