EDC-2: the endocrine society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Environmental health risks induced by interaction between phthalic acid esters (PAEs) and biological macromolecules: a review

Z Wang, J Ma, T Wang, C Qin, X Hu, A Mosa, W Ling - Chemosphere, 2023 - Elsevier
As a kind of compounds abused in industry productions, phthalic acid esters (PAEs) cause
serious problems in natural environment. PAEs pollution has penetrated into environmental …

Effect-directed analysis supporting monitoring of aquatic environments—an in-depth overview

W Brack, S Ait-Aissa, RM Burgess, W Busch… - Science of the Total …, 2016 - Elsevier
Aquatic environments are often contaminated with complex mixtures of chemicals that may
pose a risk to ecosystems and human health. This contamination cannot be addressed with …

Thyroid effects of endocrine disrupting chemicals

M Boas, U Feldt-Rasmussen, KM Main - Molecular and cellular …, 2012 - Elsevier
In recent years, many studies of thyroid-disrupting effects of environmental chemicals have
been published. Of special concern is the exposure of pregnant women and infants, as …

Develo** QSAR models with defined applicability domains on PPARγ binding affinity using large data sets and machine learning algorithms

Z Wang, J Chen, H Hong - Environmental Science & Technology, 2021 - ACS Publications
Chemicals may cause adverse effects on human health through binding to peroxisome
proliferator-activated receptor γ (PPARγ). Hence, binding affinity is useful for evaluating …

Thyroid Disruption by Bisphenol S Analogues via Thyroid Hormone Receptor β: in Vitro, in Vivo, and Molecular Dynamics Simulation Study

L Lu, T Zhan, M Ma, C Xu, J Wang… - Environmental …, 2018 - ACS Publications
Bisphenol S (4-hydroxyphenyl sulfone, BPS) is increasingly used as a bisphenol A (BPA)
alternative. The global usage of BPS and its analogues (BPSs) resulted in the frequent …

Thyroid-disrupting chemicals and brain development: an update

BB Mughal, JB Fini, BA Demeneix - Endocrine connections, 2018 - ec.bioscientifica.com
This review covers recent findings on the main categories of thyroid hormone–disrupting
chemicals and their effects on brain development. We draw mostly on epidemiological and …

Neurobehavioral deficits, diseases, and associated costs of exposure to endocrine-disrupting chemicals in the European Union

M Bellanger, B Demeneix, P Grandjean… - The Journal of …, 2015 - academic.oup.com
Context: Epidemiological studies and animal models demonstrate that endocrine-disrupting
chemicals (EDCs) contribute to cognitive deficits and neurodevelopmental disabilities …

Comparative cytotoxicity of halogenated aromatic DBPs and implications of the corresponding developed QSAR model to toxicity mechanisms of those DBPs: Binding …

Z Zhang, Q Zhu, C Huang, M Yang, J Li, Y Chen… - Water Research, 2020 - Elsevier
Halogenated aromatic disinfection byproducts (DBPs) are a new group of emerging DBPs
identified recently. They have been detected in disinfected drinking water, wastewater …

A mechanistic view of polybrominated diphenyl ether (PBDE) developmental neurotoxicity

LG Costa, R de Laat, S Tagliaferri, C Pellacani - Toxicology letters, 2014 - Elsevier
Polybrominated diphenyl ethers (PBDEs), extensively used in the past few decades as flame
retardants in a variety of consumer products, have become world-wide persistent …