Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation

CW Shields Iv, CD Reyes, GP López - Lab on a Chip, 2015 - pubs.rsc.org
Accurate and high throughput cell sorting is a critical enabling technology in molecular and
cellular biology, biotechnology, and medicine. While conventional methods can provide high …

Particle separation and sorting in microfluidic devices: a review

P Sajeesh, AK Sen - Microfluidics and nanofluidics, 2014 - Springer
Separation and sorting of micron-sized particles has great importance in diagnostics,
chemical and biological analyses, food and chemical processing and environmental …

Nanoscale lateral displacement arrays for the separation of exosomes and colloids down to 20 nm

BH Wunsch, JT Smith, SM Gifford, C Wang… - Nature …, 2016 - nature.com
Deterministic lateral displacement (DLD) pillar arrays are an efficient technology to sort,
separate and enrich micrometre-scale particles, which include parasites, bacteria, blood …

Microfluidic, marker-free isolation of circulating tumor cells from blood samples

NM Karabacak, PS Spuhler, F Fachin, EJ Lim, V Pai… - Nature protocols, 2014 - nature.com
The ability to isolate and analyze rare circulating tumor cells (CTCs) has the potential to
further our understanding of cancer metastasis and enhance the care of cancer patients. In …

Label-free cell separation and sorting in microfluidic systems

DR Gossett, WM Weaver, AJ Mach, SC Hur… - Analytical and …, 2010 - Springer
Cell separation and sorting are essential steps in cell biology research and in many
diagnostic and therapeutic methods. Recently, there has been interest in methods which …

Design of pressure-driven microfluidic networks using electric circuit analogy

KW Oh, K Lee, B Ahn, EP Furlani - Lab on a Chip, 2012 - pubs.rsc.org
This article reviews the application of electric circuit methods for the analysis of pressure-
driven microfluidic networks with an emphasis on concentration-and flow-dependent …

Inertial focusing in microfluidics

JM Martel, M Toner - Annual review of biomedical engineering, 2014 - annualreviews.org
When Segré and Silberberg in 1961 witnessed particles in a laminar pipe flow congregating
at an annulus in the pipe, scientists were perplexed and spent decades learning why such …

Inertial microfluidics for continuous particle separation in spiral microchannels

SS Kuntaegowdanahalli, AAS Bhagat, G Kumar… - Lab on a Chip, 2009 - pubs.rsc.org
In this work we report on a simple inertial microfluidic device that achieves continuous multi-
particle separation using the principle of Dean-coupled inertial migration in spiral …

Continuous flow separations in microfluidic devices

N Pamme - Lab on a Chip, 2007 - pubs.rsc.org
Biochemical sample mixtures are commonly separated in batch processes, such as filtration,
centrifugation, chromatography or electrophoresis. In recent years, however, many research …

Deterministic lateral displacement: Challenges and perspectives

A Hochstetter, R Vernekar, RH Austin, H Becker… - ACS …, 2020 - ACS Publications
The advent of microfluidics in the 1990s promised a revolution in multiple industries from
healthcare to chemical processing. Deterministic lateral displacement (DLD) is a continuous …