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Vat photopolymerization 3D printed microfluidic devices for organ-on-a-chip applications
Organs-on-a-chip, or OoCs, are microfluidic tissue culture devices with micro-scaled
architectures that repeatedly achieve biomimicry of biological phenomena. They are well …
architectures that repeatedly achieve biomimicry of biological phenomena. They are well …
Microfluidic organ‐on‐a‐chip technology for advancement of drug development and toxicology
JD Caplin, NG Granados, MR James… - Advanced …, 2015 - Wiley Online Library
In recent years, the exploitation of phenomena surrounding microfluidics has seen an
increase in popularity, as researchers have found a way to use their unique properties to …
increase in popularity, as researchers have found a way to use their unique properties to …
Development of a functional airway-on-a-chip by 3D cell printing
We used 3D cell printing to emulate an airway coupled with a naturally-derived blood vessel
network in vitro. Decellularized extracellular matrix bioink derived from porcine tracheal …
network in vitro. Decellularized extracellular matrix bioink derived from porcine tracheal …
A biomimetic multicellular model of the airways using primary human cells
Microfluidic cell cultures enable investigation of complex physiological tissue properties and
functionalities. For convenience, they are often implemented with immortalized cell lines, but …
functionalities. For convenience, they are often implemented with immortalized cell lines, but …
[HTML][HTML] Alternative lung cell model systems for toxicology testing strategies: current knowledge and future outlook
JA Moura, K Meldrum, SH Doak, MJD Clift - Seminars in Cell & …, 2023 - Elsevier
Due to the current relevance of pulmonary toxicology (with focus upon air pollution and the
inhalation of hazardous materials), it is important to further develop and implement …
inhalation of hazardous materials), it is important to further develop and implement …
[HTML][HTML] Oral mucosa-on-a-chip to assess layer-specific responses to bacteria and dental materials
The human oral mucosa hosts a diverse microbiome and is exposed to potentially toxic
biomaterials from dental restoratives. Mucosal health is partly determined by cell and tissue …
biomaterials from dental restoratives. Mucosal health is partly determined by cell and tissue …
Biomimetic microfluidic chips for toxicity assessment of environmental pollutants
X Du, J Yang - Science of The Total Environment, 2024 - Elsevier
Various types of pollutants widely present in environmental media, including synthetic and
natural chemicals, physical pollutants such as radioactive substances, ultraviolet rays, and …
natural chemicals, physical pollutants such as radioactive substances, ultraviolet rays, and …
Concise review: stem cell microenvironment on a chip: current technologies for tissue engineering and stem cell biology
Stem cells have huge potential in many therapeutic areas. With conventional cell culture
methods, however, it is difficult to achieve in vivo-like microenvironments in which a number …
methods, however, it is difficult to achieve in vivo-like microenvironments in which a number …
Temporal monitoring of differentiated human airway epithelial cells using microfluidics
The airway epithelium is exposed to a variety of harmful agents during breathing and
appropriate cellular responses are essential to maintain tissue homeostasis. Recent …
appropriate cellular responses are essential to maintain tissue homeostasis. Recent …
[HTML][HTML] Biomimetics of the pulmonary environment in vitro: A microfluidics perspective
The entire luminal surface of the lungs is populated with a complex yet confluent,
uninterrupted airway epithelium in conjunction with an extracellular liquid lining layer that …
uninterrupted airway epithelium in conjunction with an extracellular liquid lining layer that …