Per‐and polyfluoroalkyl substance toxicity and human health review: Current state of knowledge and strategies for informing future research

SE Fenton, A Ducatman, A Boobis… - Environmental …, 2021 - Wiley Online Library
Reports of environmental and human health impacts of per‐and polyfluoroalkyl substances
(PFAS) have greatly increased in the peer‐reviewed literature. The goals of the present …

PFAS exposure pathways for humans and wildlife: a synthesis of current knowledge and key gaps in understanding

AO De Silva, JM Armitage, TA Bruton… - Environmental …, 2021 - Wiley Online Library
We synthesize current understanding of the magnitudes and methods for assessing human
and wildlife exposures to poly‐and perfluoroalkyl substances (PFAS). Most human exposure …

Strategies for grou** per-and polyfluoroalkyl substances (PFAS) to protect human and environmental health

IT Cousins, JC DeWitt, J Glüge, G Goldenman… - … Science: Processes & …, 2020 - pubs.rsc.org
Grou** strategies are needed for per-and polyfluoroalkyl substances (PFAS), in part,
because it would be time and resource intensive to test and evaluate the more than 4700 …

[HTML][HTML] Insight into the binding model of per-and polyfluoroalkyl substances to proteins and membranes

L Zhao, M Teng, X Zhao, Y Li, J Sun, W Zhao… - Environment …, 2023 - Elsevier
Legacy per-and polyfluoroalkyl substances (PFASs) have elicited much concern because of
their ubiquitous distribution in the environment and the potential hazards they pose to …

[HTML][HTML] Per-and perfluoroalkyl substances alternatives, mixtures and liver function in adults: A community-based population study in China

JJ Liu, XX Cui, YW Tan, PX Dong, YQ Ou, QQ Li… - Environment …, 2022 - Elsevier
Experimental evidence has shown that per-and polyfluoroalkyl substances (PFAS)
alternatives and mixtures may exert hepatotoxic effects in animals. However …

Environmental sources, chemistry, fate, and transport of per‐and polyfluoroalkyl substances: State of the science, key knowledge gaps, and recommendations …

JL Guelfo, S Korzeniowski, MA Mills… - Environmental …, 2021 - Wiley Online Library
Abstract A Society of Environmental Toxicology and Chemistry (SETAC) Focused Topic
Meeting (FTM) on the environmental management of per‐and polyfluoroalkyl substances …

Effect of enterohepatic circulation on the accumulation of per-and polyfluoroalkyl substances: evidence from experimental and computational studies

H Cao, Z Zhou, Z Hu, C Wei, J Li, L Wang… - Environmental …, 2022 - ACS Publications
The pharmacokinetic characteristics of per-and polyfluoroalkyl substances (PFAS) affect
their distribution and bioaccumulation in biological systems. The enterohepatic circulation …

Dietary exposure to per-and polyfluoroalkyl substances: Potential health impacts on human liver

J Zhang, L Hu, H Xu - Science of the Total Environment, 2024 - Elsevier
Per-and polyfluoroalkyl substances (PFAS), dubbed “forever chemicals”, are widely present
in the environment. Environmental contamination and food contact substances are the main …

A critical review on transplacental transfer of per-and polyfluoroalkyl substances: prenatal exposure levels, characteristics, and mechanisms

D Ma, Y Lu, Y Liang, T Ruan, J Li, C Zhao… - Environmental …, 2021 - ACS Publications
Prenatal exposure to perfluoroalkyl and polyfluoroalkyl substances (PFASs) has aroused
public concerns as it can pose multiple health threats to pregnant women and cause …

Critical new insights into the binding of poly-and perfluoroalkyl substances (PFAS) to albumin protein

JL Alesio, A Slitt, GD Bothun - Chemosphere, 2022 - Elsevier
With an increasing number of health-related impacts of per-and polyfluoroalkyl substances
(PFAS) being reported, there is a pressing need to understand PFAS transport within both …