LncRNA-encoded peptides in cancer

Y Zhang - Journal of Hematology & Oncology, 2024 - Springer
Long non-coding RNAs (lncRNAs), once considered transcriptional noise, have emerged as
critical regulators of gene expression and key players in cancer biology. Recent …

Potential anticancer properties and mechanisms of thymoquinone in osteosarcoma and bone metastasis

M Homayoonfal, Z Asemi, B Yousefi - Cellular & Molecular Biology Letters, 2022 - Springer
Despite great advances, therapeutic approaches of osteosarcoma, the most prevalent class
of preliminary pediatric bone tumors, as well as bone-related malignancies, continue to …

[HTML][HTML] Mesenchymal stem cell derived exosomes as nanodrug carrier of doxorubicin for targeted osteosarcoma therapy via SDF1-CXCR4 axis

H Wei, F Chen, J Chen, H Lin, S Wang… - International journal …, 2022 - ncbi.nlm.nih.gov
Purpose The objective of this study was to investigate the antitumor activity, targeting
capability, and mechanism of the developed nanodrug consisting of doxorubicin and …

Clinical Experience and Recent Advances in the Development of Listeria-Based Tumor Immunotherapies

M Oladejo, Y Paterson, LM Wood - Frontiers in immunology, 2021 - frontiersin.org
The promise of tumor immunotherapy to significantly improve survival in patients who are
refractory to long-standing therapies, such as chemotherapy and radiation, is now being …

Risk factors, prognostic factors, and nomograms for distant metastasis in patients with newly diagnosed osteosarcoma: a population-based study

B Chen, Y Zeng, B Liu, G Lu, Z ** countries for osteosarcoma
H Tang, H Huang, J Liu, J Zhu, F Gou, J Wu - Healthcare, 2022 - mdpi.com
Osteosarcoma is a malignant tumor derived from primitive osteogenic mesenchymal cells,
which is extremely harmful to the human body and has a high mortality rate. Early diagnosis …

Alternatively spliced isoforms of the P2X7 receptor: structure, function and disease associations

SKF De Salis, L Li, Z Chen, KW Lam… - International Journal of …, 2022 - mdpi.com
The P2X7 receptor (P2X7R) is an ATP-gated membrane ion channel that is expressed by
multiple cell types. Following activation by extracellular ATP, the P2X7R mediates a broad …

Gossypetin is a novel modulator of inflammatory cytokine production and a suppressor of osteosarcoma cell growth

C Proença, AT Rufino, I Santos, HMT Albuquerque… - Antioxidants, 2023 - mdpi.com
Osteosarcoma (OS) is a common childhood sarcoma, and its treatment is hindered by
adverse effects, chemoresistance, and recurrence. Interleukin (IL)-6 production by tumors …

Interactions between circRNAs and miR-141 in cancer: from pathogenesis to diagnosis and therapy

M Guz, W Jeleniewicz, M Cybulski - International Journal of Molecular …, 2023 - mdpi.com
The function of non-coding RNAs (ncRNAs) in the pathogenesis and development of cancer
is indisputable. Molecular mechanisms underlying carcinogenesis involve the aberrant …

Multifunctional 3D-printed bioceramic scaffolds: Recent strategies for osteosarcoma treatment

X Liu, Y Liu, L Qiang, Y Ren, Y Lin… - Journal of Tissue …, 2023 - journals.sagepub.com
Osteosarcoma is the most prevalent bone malignant tumor in children and teenagers. The
bone defect, recurrence, and metastasis after surgery severely affect the life quality of …