Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseases

AN Saiyed, AR Vasavada, SRK Johar - Future Journal of Pharmaceutical …, 2022 - Springer
Background Researchers now have a new avenue to investigate when it comes to miRNA-
based therapeutics. miRNAs have the potential to be valuable biomarkers for disease …

Molecular mechanism of miRNA mediated biosynthesis of secondary metabolites in medicinal plants

H Li, Z Guo, M Xu, J Zhao, D Xu - Plant Physiology and Biochemistry, 2024 - Elsevier
Plant secondary metabolites are important raw materials for the pharmaceutical industry,
and their biosynthetic processes are subject to diverse and precise regulation by miRNA …

Identification of miRNAs and Their Target Genes Involved in the Biosynthesis of Flower Color and Scent in Rosa canina L.

P Jariani, AA Shahnejat-Bushehri, R Naderi… - Iranian Journal of …, 2024 - Springer
Rose flowers are known for their diverse and attractive colors and scents, which are
influenced by the expression of phyto-miRNAs. These are small non-coding RNAs that …

Applications of some advanced sequencing, analytical, and computational approaches in medicinal plant research: a review

D Singh, N Mittal, S Verma, A Singh… - Molecular Biology …, 2024 - Springer
The potential active chemicals found in medicinal plants, which have long been employed
as natural medicines, are abundant. Exploring the genes responsible for producing these …

Predictive Role of Cluster Bean (Cyamopsis tetragonoloba) Derived miRNAs in Human and Cattle Health

S Sahu, AR Rao, TK Sahu, J Pandey, S Varshney… - Genes, 2024 - mdpi.com
MicroRNAs (miRNAs) are small non-coding conserved molecules with lengths varying
between 18-25nt. Plants miRNAs are very stable, and probably they might have been …

MicroRNAs from Holarrhena pubescens stems: Identification by small RNA Sequencing and their Potential Contribution to Human Gene Targets

TS Trivedi, MP Patel, V Nanavaty, AU Mankad… - Functional & Integrative …, 2023 - Springer
Holarrhena pubescens is an effective medicinal plant from the Apocynaceae family, widely
distributed over the Indian subcontinent and extensively used by Ayurveda and ethno …

[HTML][HTML] MicroRNAs in medicinal plants

M Sun, S Xu, Y Mei, J Li, Y Gu, W Zhang… - International journal of …, 2022 - mdpi.com
Medicinal plant microRNAs (miRNAs) are an endogenous class of small RNA central to the
posttranscriptional regulation of gene expression. Biosynthetic research has shown that the …

Identifying potential human and medicinal plant microRNAs against SARS-CoV-2 3′ UTR region: A computational genomics assessment

N Mangukia, P Rao, K Patel, H Pandya… - Computers in Biology and …, 2021 - Elsevier
The coronavirus disease of 2019 (COVID-19) began as an outbreak and has taken a toll on
human lives. The current pandemic requires scientific attention; hence we designed a …

A novel insight of Picrorhiza kurroa miRNAs in human cystic fibrosis: A transcriptome-wide cross-kingdom study

TS Trivedi, N Mangukia, M Bhavsar, AU Mankad… - Human Gene, 2023 - Elsevier
Abstract Picrorhiza kurroa Royle ex Benth., a well-known traditional herb from the
Scrophulariaceae family, has a distinguished reputation amongst indigenous medicinal …

Small RNA sequencing and identification of papaya (Carica papaya L.) miRNAs with potential cross-kingdom human gene targets

N Jha, N Mangukia, H Gadhavi, M Patel… - Molecular Genetics and …, 2022 - Springer
Several studies have demonstrated potential role of plant-derived miRNAs in cross-kingdom
species relationships by transferring into non-plant host cells to regulate certain host cellular …