Pesticides and human chronic diseases: evidences, mechanisms, and perspectives

S Mostafalou, M Abdollahi - Toxicology and applied pharmacology, 2013 - Elsevier
Along with the wide use of pesticides in the world, the concerns over their health impacts are
rapidly growing. There is a huge body of evidence on the relation between exposure to …

Neuroactive insecticides: targets, selectivity, resistance, and secondary effects

JE Casida, KA Durkin - Annual review of entomology, 2013 - annualreviews.org
Neuroactive insecticides are the principal means of protecting crops, people, livestock, and
pets from pest insect attack and disease transmission. Currently, the four major nerve targets …

In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer

M Momcilovic, A Jones, ST Bailey, CM Waldmann, R Li… - Nature, 2019 - nature.com
Mitochondria are essential regulators of cellular energy and metabolism, and have a crucial
role in sustaining the growth and survival of cancer cells. A central function of mitochondria …

Natural products in crop protection

FE Dayan, CL Cantrell, SO Duke - Bioorganic & medicinal chemistry, 2009 - Elsevier
The tremendous increase in crop yields associated with the 'green'revolution has been
possible in part by the discovery and utilization of chemicals for pest control. However …

Using rotenone to model Parkinson's disease in mice: a review of the role of pharmacokinetics

J Innos, MA Hickey - Chemical research in toxicology, 2021 - ACS Publications
Rotenone is a naturally occurring toxin that inhibits complex I of the mitochondrial electron
transport chain. Several epidemiological studies have shown an increased risk of …

The role of Nrf2 in neural stem/progenitors cells: From maintaining stemness and self-renewal to promoting differentiation capability and facilitating therapeutic …

H Kahroba, B Ramezani, H Maadi, MR Sadeghi… - Ageing research …, 2021 - Elsevier
Neurodegenerative diseases (NDs) cause progressive loss of neurons in nervous system.
NDs are categorized as acute NDs such as stroke and head injury, besides chronic NDs …

Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention

MG Tansey, MK McCoy, TC Frank-Cannon - Experimental neurology, 2007 - Elsevier
Most acute and chronic neurodegenerative conditions are accompanied by
neuroinflammation; yet the exact nature of the inflammatory processes and whether they …

Managing non‐native fish in the environment

JR Britton, RE Gozlan, GH Copp - Fish and fisheries, 2011 - Wiley Online Library
Non‐native fishes are frequently used to enhance aquaculture and fisheries; if introduced
into the wider environment, then the majority will have negligible effects on native …

Nrf2 as regulator of innate immunity: a molecular Swiss army knife!

M Battino, F Giampieri, F Pistollato, A Sureda… - Biotechnology …, 2018 - Elsevier
Organisms are constantly exposed to a broad range of pathological and stress-inducing
agents, allergens and environmental chemicals that can induce infections, toxicity or other …

Natural products are a promising source for anthelmintic drug discovery

KLTD Jayawardene, EA Palombo, PR Boag - Biomolecules, 2021 - mdpi.com
Parasitic nematodes infect almost all forms of life. In the human context, parasites are one of
the major causative factors for physical and intellectual growth retardation in the develo** …