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Regulation of microtubule dynamics, mechanics and function through the growing tip
Microtubule dynamics and their control are essential for the normal function and division of
all eukaryotic cells. This plethora of functions is, in large part, supported by dynamic …
all eukaryotic cells. This plethora of functions is, in large part, supported by dynamic …
Mechanisms of microtubule organization in differentiated animal cells
A Akhmanova, LC Kapitein - Nature Reviews Molecular Cell Biology, 2022 - nature.com
Microtubules are polarized cytoskeletal filaments that serve as tracks for intracellular
transport and form a scaffold that positions organelles and other cellular components and …
transport and form a scaffold that positions organelles and other cellular components and …
[HTML][HTML] The cytoskeleton—a complex interacting meshwork
T Hohmann, F Dehghani - Cells, 2019 - mdpi.com
The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …
Microtubule dynamics: an interplay of biochemistry and mechanics
Microtubules are dynamic polymers of αβ-tubulin that are essential for intracellular
organization, organelle trafficking and chromosome segregation. Microtubule growth and …
organization, organelle trafficking and chromosome segregation. Microtubule growth and …
CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC
Abstract γ-Tubulin ring complex (γ-TuRC) is the major microtubule-nucleating factor. After
nucleation, microtubules can be released from γ-TuRC and stabilized by other proteins …
nucleation, microtubules can be released from γ-TuRC and stabilized by other proteins …
The mechanism of acentrosomal spindle assembly in human oocytes
T Wu, J Dong, J Fu, Y Kuang, B Chen, H Gu, Y Luo… - Science, 2022 - science.org
Meiotic spindle assembly ensures proper chromosome segregation in oocytes. However,
the mechanisms behind spindle assembly in human oocytes remain largely unknown. We …
the mechanisms behind spindle assembly in human oocytes remain largely unknown. We …
Control of microtubule organization and dynamics: two ends in the limelight
A Akhmanova, MO Steinmetz - Nature reviews Molecular cell biology, 2015 - nature.com
Microtubules have fundamental roles in many essential biological processes, including cell
division and intracellular transport. They assemble and disassemble from their two ends …
division and intracellular transport. They assemble and disassemble from their two ends …
Mitotic spindle assembly in animal cells: a fine balancing act
The mitotic spindle has a crucial role in ensuring the accurate segregation of chromosomes
into the two daughter cells during cell division, which is paramount for maintaining genome …
into the two daughter cells during cell division, which is paramount for maintaining genome …
The centrosome is a selective condensate that nucleates microtubules by concentrating tubulin
Centrosomes are non-membrane-bound compartments that nucleate microtubule arrays.
They consist of nanometer-scale centrioles surrounded by a micron-scale, dynamic …
They consist of nanometer-scale centrioles surrounded by a micron-scale, dynamic …
Fungal morphogenesis, from the polarized growth of hyphae to complex reproduction and infection structures
Filamentous fungi constitute a large group of eukaryotic microorganisms that grow by
forming simple tube-like hyphae that are capable of differentiating into more-complex …
forming simple tube-like hyphae that are capable of differentiating into more-complex …