Antibacterial pyrazoles: Tackling resistant bacteria
MA Alam - Future Medicinal Chemistry, 2022 - Taylor & Francis
Bacterial resistance to antibiotics threatens our progress in healthcare, modern medicine,
food production and ultimately life expectancy. Antibiotic resistance is a global concern …
food production and ultimately life expectancy. Antibiotic resistance is a global concern …
[HTML][HTML] The bioactivity of benzenesulfonyl hydrazones: A short review
Ł Popiołek - Biomedicine & Pharmacotherapy, 2021 - Elsevier
The synthesis and biological activity evaluation of benzenesulfonyl hydrazones is quite
frequently encountered in scientific literature. This class of compounds is very interesting …
frequently encountered in scientific literature. This class of compounds is very interesting …
Aloe emodin-conjugated sulfonyl hydrazones as novel type of antibacterial modulators against S. aureus 25923 through multifaceted synergistic effects
Z Deng, RRY Bheemanaboina, Y Luo, CH Zhou - Bioorganic Chemistry, 2022 - Elsevier
Aloe emodin-conjugated sulfonyl hydrazones were designed and synthesized as novel type
of antibacterial modulators. Aloe emodin benzenesulfonyl hydrazone 5a (AEBH-5a) was …
of antibacterial modulators. Aloe emodin benzenesulfonyl hydrazone 5a (AEBH-5a) was …
Development of new antimycobacterial sulfonyl hydrazones and 4-methyl-1, 2, 3-thiadiazole-based hydrazone derivatives
Fifteen 4-methyl-1, 2, 3-thiadiazole-based hydrazone derivatives 3a–d and sulfonyl
hydrazones 5a–k were synthesized. They were characterized by 1H-NMR, 13C NMR, and …
hydrazones 5a–k were synthesized. They were characterized by 1H-NMR, 13C NMR, and …
Hydrazinosulfonylation of aryl electrophiles: a straightforward approach for the synthesis of aryl N-aminosulfonamides
CY Hsu, AKO Aldulaimi, H Bahir, AH Adhab… - RSC …, 2023 - pubs.rsc.org
In recent years, the direct hydrazinosulfonylation of aryl electrophiles with SO2 and
hydrazines has emerged as an efficient and versatile method for the synthesis of aryl N …
hydrazines has emerged as an efficient and versatile method for the synthesis of aryl N …
Linking quinoline ring to 5-nitrofuran moiety via sulfonyl hydrazone bridge: Synthesis, structural characterization, DFT studies, and evaluation of antibacterial and …
In the present work, we report the synthesis, structural characterization, and computational
studies of (E)-N'-((5-nitrofuran-2-yl) methylene) quinoline-8-sulfonohydrazide (QNF) as a …
studies of (E)-N'-((5-nitrofuran-2-yl) methylene) quinoline-8-sulfonohydrazide (QNF) as a …
Design, synthesis and mechanistic studies of benzophenones hydrazone derivatives as cathepsin inhibitors
A novel series of benzophenone hydrazone derivatives were synthesized and evaluated for
their antiproliferative activity. The thiosemicarbazone derivative 5c and guanylhydrazone …
their antiproliferative activity. The thiosemicarbazone derivative 5c and guanylhydrazone …
Synthesis, anti-ferroptosis, anti-quorum sensing, antibacterial and DNA interaction studies of chromene-hydrazone derivatives
AJ Ressler, M Frate, A Hontoria, A Ream… - Bioorganic & medicinal …, 2023 - Elsevier
Nineteen chromene-hydrazone derivatives containing a variety of structural modifications on
the hydrazone moiety were synthesized. Structure-activity correlations were investigated to …
the hydrazone moiety were synthesized. Structure-activity correlations were investigated to …
[HTML][HTML] Approachable Synthetic Methodologies for Second-Generation β-Lactamase Inhibitors: A Review
Some antibiotics that are frequently employed are β-lactams. In light of the hydrolytic
process of β-lactamase, found in Gram-negative bacteria, inhibitors of β-lactamase (BLIs) …
process of β-lactamase, found in Gram-negative bacteria, inhibitors of β-lactamase (BLIs) …
Fungal secondary metabolites/dicationic pyridinium iodide combinations in combat against multi-drug resistant microorganisms
The spread of antibiotic-resistant opportunistic microbes is a huge socioeconomic burden
and a growing concern for global public health. In the current study, two endophytic fungal …
and a growing concern for global public health. In the current study, two endophytic fungal …