Monoligated palladium (0) species, L1Pd (0), have emerged as the most active catalytic
species in the cross-coupling cycle. Today, there are methods available to generate the …

The story of C− C bond formation includes several reactions, and surely Suzuki‐Miyaura is
among the most outstanding ones. Herein, a brief historical overview of insights regarding …

The first now-named Stille reaction was published 38 years ago, and the last comprehensive
revision of this catalysis was in 2004. Since then, the knowledge of the different steps of the …

In homogeneous catalysis, the main emphasis on improving catalyst performance (rate,
yield and selectivity) is directed towards manipulation of the ligands. The steric and …

The oxidative addition (OA) of organic electrophiles to Pd (0) is a fundamental step in
organopalladium chemistry and plays a key role in palladium-catalyzed cross-coupling …

Suzuki–Miyaura cross-coupling reactions of heteroaryl polyhalides with aryl boronates are
surveyed. Drawing on data from literature sources as well as bespoke searches of Pfizer's …

The development of metal complexes that function as both photocatalyst and cross‐coupling
catalyst remains a challenging research topic. So far, progress has been shown in palladium …

The result of the application of different approaches based on the ideal gas/rigid
rotor/harmonic oscillator (IGRRHO) model, commonly used in popular software packages …

We describe a detailed investigation into why bulky ligands─ those that enable catalysis at
“12 e–” Pd0─ tend to promote overfunctionalization during Pd-catalyzed cross-couplings of …

As the accuracy of computational chemistry increases, and the advent of more powerful
computers decreases the amount of time required to perform complex calculations, the use …