New advances in general biomedical applications of PAMAM dendrimers
Dendrimers are nanoscopic compounds, which are monodispersed, and they are generally
considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by …
considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by …
Poly (amidoamine)(PAMAM) dendrimer mediated delivery of drug and pDNA/siRNA for cancer therapy
J Li, H Liang, J Liu, Z Wang - International journal of pharmaceutics, 2018 - Elsevier
Abstract Poly (amidoamine)(PAMAM) dendrimers are well-defined, highly branched
macromolecules with numerous active amine groups on the surface. Because of their …
macromolecules with numerous active amine groups on the surface. Because of their …
Safety challenges and application strategies for the use of dendrimers in medicine
X Li, A Naeem, S **ao, L Hu, J Zhang, Q Zheng - Pharmaceutics, 2022 - mdpi.com
Dendrimers are used for a variety of applications in medicine but, due to their host–guest
and entrapment characteristics, are particularly used for the delivery of genes and drugs …
and entrapment characteristics, are particularly used for the delivery of genes and drugs …
Smart AS1411-aptamer conjugated pegylated PAMAM dendrimer for the superior delivery of camptothecin to colon adenocarcinoma in vitro and in vivo
In the current study camptothecin-loaded pegylated PAMAM dendrimer were synthesized
and were functionalized with AS1411 anti-nucleolin aptamers for site-specific targeting …
and were functionalized with AS1411 anti-nucleolin aptamers for site-specific targeting …
Dendrimer based theranostic nanostructures for combined chemo-and photothermal therapy of liver cancer cells in vitro
Here we report the synthesis of multifunctional nanocarriers based on PAMAM dendrimers
generation (G) 4.0, 5.0 and 6.0 fixed to polydopamine (PDA) coated magnetite nanoparticles …
generation (G) 4.0, 5.0 and 6.0 fixed to polydopamine (PDA) coated magnetite nanoparticles …
[HTML][HTML] Polymers as efficient non-viral gene delivery vectors: the role of the chemical and physical architecture of macromolecules
M Khan - Polymers, 2024 - mdpi.com
Gene therapy is the technique of inserting foreign genetic elements into host cells to achieve
a therapeutic effect. Although gene therapy was initially formulated as a potential remedy for …
a therapeutic effect. Although gene therapy was initially formulated as a potential remedy for …
[HTML][HTML] Starburst pamam dendrimers: Synthetic approaches, surface modifications, and biomedical applications
R Kharwade, S More, A Warokar, P Agrawal… - Arabian Journal of …, 2020 - Elsevier
Dendrimers are having novel three dimensional, synthetic hyperbranched, nano-polymeric
structure. Among all of the dendrimers, Poly-amidoamine (PAMAM) dendrimer are used …
structure. Among all of the dendrimers, Poly-amidoamine (PAMAM) dendrimer are used …
Magnetic solid-phase extraction of non-steroidal anti-inflammatory drugs from environmental water samples using polyamidoamine dendrimer functionalized with …
A novel polyamidoamine dendrimer functionalized with Fe 3 O 4 nanoparticles (Fe 3 O 4@
PAMAM) had been fabricated and used as magnetic solid-phase extraction (MSPE) …
PAMAM) had been fabricated and used as magnetic solid-phase extraction (MSPE) …
Synthesis of folic acid-conjugated glycodendrimer with magnetic β-cyclodextrin core as a pH-responsive system for tumor-targeted co-delivery of doxorubicin and …
S Karimi, H Namazi - Colloids and Surfaces A: Physicochemical and …, 2021 - Elsevier
One of the most important applications of nanotechnology in cancer treatment involves the
design of magnetic nanocomposites for the targeted delivery of anticancer drugs to cancer …
design of magnetic nanocomposites for the targeted delivery of anticancer drugs to cancer …
Recent advances in multifunctional dendrimer-based nanoprobes for breast cancer theranostics
Breast cancer (BC) undoubtedly is one of the most common type of cancers amongst
women, which causes about 5 million deaths annually. The treatments and diagnostic …
women, which causes about 5 million deaths annually. The treatments and diagnostic …