Nanomaterials in proteomics

N Sun, H Wu, X Shen, C Deng - Advanced Functional Materials, 2019 - Wiley Online Library
For a deep understanding of the human proteome, the first crucial step is always the
effective separation of targeted proteins/peptides from complex samples. In mass …

Associative and Dissociative Processes in Non‐Covalent Polymer‐Mediated Intracellular Protein Delivery

ND Posey, GN Tew - Chemistry–An Asian Journal, 2018 - Wiley Online Library
Functional protein delivery has created new opportunities for studying intracellular
processes and discovering new therapeutics. To that end, researchers have pursued …

Pyrene-based covalent organic framework for selective enrichment of hydrophobic peptides with simultaneous proteins exclusion

A Irfan, T Wang, A Wang, X **g, L Yang, G Zhu - Analytica chimica acta, 2022 - Elsevier
Owing to the desirable structures, covalent organic frameworks (COFs) have emerged as
promising porous crystalline materials in bioanalytical and biomedical science. However …

The role of cargo binding strength in polymer-mediated intracellular protein delivery

ND Posey, CR Hango, LM Minter… - Bioconjugate Chemistry, 2018 - ACS Publications
Delivering proteins into the intracellular environment is a critical step toward probing vital
cellular processes for the purposes of ultimately develo** new therapeutics. Polymeric …

Self-assembly of amino acid-based random copolymers for antibacterial application and infection treatment as nanocarriers

J Zhu, H Han, F Li, X Wang, J Yu, CC Chu… - Journal of colloid and …, 2019 - Elsevier
Bacterial infection is one of the most significant complications worldwide and has been one
of the main factors of morbidity and mortality for the chronic wounds. Considering the …

Combined Simulation and Experimental Study of Polyampholyte Solution Properties: Effects of Charge Ratio, Hydrophobic Groups, and Polymer Concentration

W Zhang, Y Ma, ND Posey, MJ Lueckheide… - …, 2022 - ACS Publications
Polyampholytes are polymers with both cationic and anionic monomers that have many
features in common with proteins. These molecules have many applications associated with …

Disulfide crosslinking and helical coiling of peptide micelles facilitate the formation of a printable hydrogel

X Yang, Y Wang, W Qi, R **ng, X Yang… - Journal of Materials …, 2019 - pubs.rsc.org
We report that the helical coiling of micelles induced by disulfide crosslinking in a lyotropic
peptide liquid crystal leads to the formation of a printable hydrogel. The (9 …

Efficient colorimetric detection of cyanide ions using hemicyanine-based polymeric probes with detection-induced self-assembly in water

JM Bak, M Gupta, SH Jung, H Lee - Polymer, 2021 - Elsevier
The design and synthesis of hemicyanine-based water-soluble polymeric probes for
colorimetric detection of CN− ions, which is accompanied by detection-induced self …

Potential of Liquid Extraction Surface Analysis Mass Spectrometry (LESA—MS) for the Characterization of Polymer-Based Materials

A Issart, J Szpunar - Polymers, 2019 - mdpi.com
Liquid extraction surface analysis mass spectrometry (LESA-MS) is a direct analysis method
suitable for the analysis of polymers. It is based on a fast and efficient extraction of polymer …

Polymeric nanoassemblies for enrichment and detection of peptides and proteins in human breast milk

B Zhao, J Gao, MAC Serrano, KF Arcaro… - Analytical and …, 2020 - Springer
Human breast milk is an understudied biological fluid that may be useful for early detection
of breast cancer. Methods for enriching and detecting biomarkers in human breast milk …