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Interplay between mechanics and signalling in regulating cell fate
Mechanical signalling affects multiple biological processes during development and in adult
organisms, including cell fate transitions, cell migration, morphogenesis and immune …
organisms, including cell fate transitions, cell migration, morphogenesis and immune …
Insight into cellular uptake and intracellular trafficking of nanoparticles
Nanoparticle science is rapidly changing the landscape of various scientific fields and
defining new technological platforms. This is perhaps even more evident in the field of …
defining new technological platforms. This is perhaps even more evident in the field of …
Advances in fatty acids nutrition in dairy cows: from gut to cells and effects on performance
High producing dairy cows generally receive in the diet up to 5–6% of fat. This is a relatively
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …
Bacterial membranes: structure, domains, and function
The bacterial cytoplasmic membrane is composed of roughly equal proportions of lipids and
proteins. The main lipid components are phospholipids, which vary in acyl chain length …
proteins. The main lipid components are phospholipids, which vary in acyl chain length …
Mechanosensitive membrane domains regulate calcium entry in arterial endothelial cells to protect against inflammation
Endothelial cells (ECs) in the descending aorta are exposed to high laminar shear stress,
and this supports an antiinflammatory phenotype. High laminar shear stress also induces …
and this supports an antiinflammatory phenotype. High laminar shear stress also induces …
Multifaceted cargo recruitment and release from artificial membraneless organelles
Liquid‐liquid phase separation (LLPS) drives membraneless organelles (MLOs) formation
for organizing biomolecules. Artificial MLOs (AMLOs) have been constructed mostly via the …
for organizing biomolecules. Artificial MLOs (AMLOs) have been constructed mostly via the …
Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain
Biological membranes are partitioned into functional zones termed membrane
microdomains, which contain specific lipids and proteins,–. The composition and …
microdomains, which contain specific lipids and proteins,–. The composition and …
[HTML][HTML] GPCRs in intracellular compartments: new targets for drug discovery
I Fasciani, M Carli, F Petragnano, F Colaianni, G Aloisi… - Biomolecules, 2022 - mdpi.com
The architecture of eukaryotic cells is defined by extensive membrane-delimited
compartments, which entails separate metabolic processes that would otherwise interfere …
compartments, which entails separate metabolic processes that would otherwise interfere …
Defining raft domains in the plasma membrane
Many plasma membrane (PM) functions depend on the cholesterol concentration in the PM
in strikingly nonlinear, cooperative ways: fully functional in the presence of physiological …
in strikingly nonlinear, cooperative ways: fully functional in the presence of physiological …
[HTML][HTML] Four-color single-molecule imaging with engineered tags resolves the molecular architecture of signaling complexes in the plasma membrane
Localization and tracking of individual receptors by single-molecule imaging opens unique
possibilities to unravel the assembly and dynamics of signaling complexes in the plasma …
possibilities to unravel the assembly and dynamics of signaling complexes in the plasma …