[HTML][HTML] Inflammation and colorectal cancer: a meta-analysis of the prognostic significance of the systemic immune–inflammation index (SII) and the systemic …

O Menyhart, JT Fekete, B Győrffy - International Journal of Molecular …, 2024 - mdpi.com
The overall prognosis for colorectal cancer (CRC) remains challenging as the survival time
varies widely, even in patients with the same stage of disease. Recent studies suggest …

Colorectal cancer: Recent advances in management and treatment

H Fadlallah, J El Masri, H Fakhereddine… - World journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common cancer worldwide, and the second most
common cause of cancer-related death. In 2020, the estimated number of deaths due to …

Epidermal growth factor receptor targeting in colorectal carcinoma: antibodies and patient-derived organoids as a smart model to study therapy resistance

S Tardito, S Matis, MR Zocchi, R Benelli… - International Journal of …, 2024 - mdpi.com
Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide.
Therefore, the need for new therapeutic strategies is still a challenge. Surgery and …

Exploring the role of Fusobacterium nucleatum in colorectal cancer: implications for tumor proliferation and chemoresistance

L Dadgar-Zankbar, Z Elahi, A Shariati… - Cell Communication and …, 2024 - Springer
Fusobacterium nucleatum (Fn) has been extensively studied for its connection to colorectal
cancer (CRC) and its potential role in chemotherapy resistance. Studies indicate that Fn is …

Unraveling the complexities of colorectal cancer and its promising therapies–An updated review

S Saha, S Ghosh, S Ghosh, S Nandi… - International …, 2024 - Elsevier
Colorectal cancer (CRC) continues to be a global health concern, necessitating further
research into its complex biology and innovative treatment approaches. The etiology …

[PDF][PDF] Precision medicine and immunotherapy advances transforming colorectal cancer treatment

TA Addissouky, IE El Sayed, MM Ali… - Journal of …, 2024 - researchgate.net
Background Colorectal cancer (CRC) remains one of the most prevalent cancers and
leading causes of cancer mortality worldwide. Global disease burden has risen in tandem …

[HTML][HTML] Plasma-Derived Extracellular Vesicles and Non-Extracellular Vesicle Components from APCMin/+ Mice Promote Pro-Tumorigenic Activities and Activate …

LA Arteaga-Blanco, AE Evans, DA Dixon - Cells, 2024 - mdpi.com
Colorectal cancer (CRC) is the third most prevalent cancer worldwide. Current studies have
demonstrated that tumor-derived extracellular vesicles (EVs) from different cancer cell types …

Resistance to 5-fluorouracil: The molecular mechanisms of development in colon cancer cells

N Radenković, D Nikodijević, J Jovankić… - European journal of …, 2024 - Elsevier
Colon cancer is a significant health problem worldwide as it is one of the most common and
deadliest cancers. The standard approach for the treatment of colon cancer is 5-fluorouracil …

NF-κB pathway and angiogenesis: insights into colorectal cancer development and therapeutic targets

A Bahrami, A Khalaji, M Bahri Najafi, S Sadati… - European Journal of …, 2024 - Springer
Colorectal cancer (CRC) is currently ranked as the third most common type of cancer,
contributing significantly to mortality and morbidity worldwide. Epigenetic and genetic …

[HTML][HTML] The roles of rac1 and rac1b in colorectal cancer and their potential contribution to cetuximab resistance

CC Wahoski, B Singh - Cancers, 2024 - mdpi.com
Simple Summary Cetuximab is a treatment widely used to treat advanced, metastatic
colorectal cancer (CRC), and it works by blocking epidermal growth factor receptor …