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Targeting anoikis resistance as a strategy for cancer therapy
Y Wang, S Cheng, JS Fleishman, J Chen, H Tang… - Drug Resistance …, 2024 - Elsevier
Anoikis, known as matrix detachment-induced apoptosis or detachment-induced cell death,
is crucial for tissue development and homeostasis. Cancer cells develop means to evade …
is crucial for tissue development and homeostasis. Cancer cells develop means to evade …
Regulation and tumor‐suppressive function of the miR‐379/miR‐656 (C14MC) cluster in cervical cancer
Cervical cancer (CC) is a key contributor to cancer‐related mortality in several countries.
The identification of molecular markers and the underlying mechanism may help improve …
The identification of molecular markers and the underlying mechanism may help improve …
Remodeling of tumor microenvironment by cellular senescence and immunosenescence in cervical cancer
Y He, Y Qiu, X Yang, G Lu, SS Zhao - Seminars in Cancer Biology, 2024 - Elsevier
Cellular senescence is a response to various stress signals, which is characterized by stable
cell cycle arrest, alterations in cellular morphology, metabolic reprogramming and …
cell cycle arrest, alterations in cellular morphology, metabolic reprogramming and …
Bisphenol A exposure modulates reproductive and endocrine system, mitochondrial function and cellular senescence in female adult rats: a hallmarks of polycystic …
Bisphenol A (BPA) mimics estrogen and consequently suspected to be detrimental to female
reproductive system. Biomonitoring confirms the BPA burden in body leading to a complex …
reproductive system. Biomonitoring confirms the BPA burden in body leading to a complex …
DOC2B is a negative regulator of Wnt/β-catenin signaling pathway in cervical cancer
DOC2B is a ubiquitously expressed isoform of the double C-2 protein family that requires Ca
2+ for most of its physiological functions. Initial findings have indicated that DOC2B …
2+ for most of its physiological functions. Initial findings have indicated that DOC2B …
Double C-2 like domain beta (DOC2B) induces calcium dependent oxidative stress to promote lipotoxicity and mitochondrial dysfunction for its tumor suppressive …
Mitochondria are biosynthetic and bioenergetic organelles that regulate many biological
processes, including metabolism, oxidative stress, and cell death. Cervical cancer (CC) cells …
processes, including metabolism, oxidative stress, and cell death. Cervical cancer (CC) cells …
Biological functions of extracellular vesicle double C2-like domain beta in cervical cancer
Abstract Double C-2 Like Domain Beta (DOC2B) located at 17q13. 3 prevents metastasis by
senescence induction and epithelial to mesenchymal transition inhibition in cervical cancer …
senescence induction and epithelial to mesenchymal transition inhibition in cervical cancer …
Goji berry (Lycium barbarum) inhibits the proliferation, adhesion, and migration of oral cancer cells by inhibiting the ERK, AKT, and CyclinD cell signaling pathways …
Background: Lycium barbarum (L. barbarum), popularly referred to as Goji berry, is a
promising herb known for its powerful anti-antioxidant, antibacterial, and anti-inflammatory …
promising herb known for its powerful anti-antioxidant, antibacterial, and anti-inflammatory …
[HTML][HTML] A Novel Role for DOC2B in Ameliorating Palmitate-Induced Glucose Uptake Dysfunction in Skeletal Muscle Cells via a Mechanism Involving β-AR Agonism …
J Hwang, R Balakrishnan, E Oh, R Veluthakal… - International Journal of …, 2023 - mdpi.com
Diet-related lipotoxic stress is a significant driver of skeletal muscle insulin resistance (IR)
and type 2 diabetes (T2D) onset. β2-adrenergic receptor (β-AR) agonism promotes insulin …
and type 2 diabetes (T2D) onset. β2-adrenergic receptor (β-AR) agonism promotes insulin …
Integrated bioinformatic analysis to understand the association between phthalate exposure and breast cancer progression
Phthalates have been extensively used as plasticizers while manufacturing plastic-based
consumer products. Estradiol mimicking properties and association studies suggest …
consumer products. Estradiol mimicking properties and association studies suggest …