Tumor-derived exosomes and their role in cancer progression

TL Whiteside - Advances in clinical chemistry, 2016 - Elsevier
Tumor cells actively produce, release, and utilize exosomes to promote tumor growth.
Mechanisms through which tumor-derived exosomes subserve the tumor are under intense …

Extracellular vesicles as tools and targets in therapy for diseases

MA Kumar, SK Baba, HQ Sadida… - Signal transduction and …, 2024 - nature.com
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

Exosomes and tumor-mediated immune suppression

TL Whiteside - The Journal of clinical investigation, 2016 - Am Soc Clin Investig
Tumor-derived exosomes (TEX) are harbingers of tumor-induced immune suppression: they
carry immunosuppressive molecules and factors known to interfere with immune cell …

Proteomic profiling of extracellular vesicles allows for human breast cancer subty**

S Rontogianni, E Synadaki, B Li, MC Liefaard… - Communications …, 2019 - nature.com
Extracellular vesicles (EVs) are a potential source of disease-associated biomarkers for
diagnosis. In breast cancer, comprehensive analyses of EVs could yield robust and reliable …

Focus on extracellular vesicles: new frontiers of cell-to-cell communication in cancer

C Ciardiello, L Cavallini, C Spinelli, J Yang… - International journal of …, 2016 - mdpi.com
Extracellular Vesicles (EVs) have received considerable attention in recent years, both as
mediators of intercellular communication pathways that lead to tumor progression, and as …

Role of sphingolipids in the biogenesis and biological activity of extracellular vesicles

C Verderio, M Gabrielli, P Giussani - Journal of lipid research, 2018 - ASBMB
Extracellular vesicles (EVs) are membrane vesicles released by both eukaryotic and
prokaryotic cells; they not only serve physiological functions, such as disposal of cellular …

“Exosomics”—a review of biophysics, biology and biochemistry of exosomes with a focus on human breast milk

C de la Torre Gomez, RV Goreham… - Frontiers in …, 2018 - frontiersin.org
Exosomes are biomolecular nanostructures released from cells. They carry specific
biomolecular information and are mainly researched for their exquisite properties as a …

Current status of circulating tumor cells, circulating tumor DNA, and exosomes in breast cancer liquid biopsies

M Tellez-Gabriel, E Knutsen, M Perander - International Journal of …, 2020 - mdpi.com
Breast cancer is the most common cancer among women worldwide. Although the five-, ten-
and fifteen-year survival rates are good for breast cancer patients diagnosed with early …

The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells

D Choi, L Montermini, DK Kim, B Meehan… - Molecular & Cellular …, 2018 - ASBMB
Glioblastoma multiforme (GBM) is a highly aggressive and heterogeneous form of primary
brain tumors, driven by a complex repertoire of oncogenic alterations, including the …

Intercellular vesicular transfer by exosomes, microparticles and oncosomes-implications for cancer biology and treatments

R Jaiswal, LM Sedger - Frontiers in oncology, 2019 - frontiersin.org
Intercellular communication is a normal feature of most physiological interactions between
cells in healthy organisms. While cells communicate directly through intimate physiology …