Vascular disease was for a long time considered a disease of the old age, but it is becoming
increasingly clear that a cumulus of factors can cause early vascular aging (EVA) …

Over the last decades, childhood and adolescence have emerged as an important window
of opportunity to prevent atherosclerotic cardiovascular disease (ASCVD) later in life. Here …

Tryptophan (Trp) is an essential amino acid, whose metabolism is a key gatekeeper of
intestinal homeostasis. Yet, its systemic effects, particularly on atherosclerosis, remain …

Disruption of intestinal homeostasis is an important event in the development of
inflammatory bowel disease (IBD), and genistein (GEN) is a candidate medicine to prevent …

Cardiovascular disease (CVD) is one of the major causes of mortality worldwide.
Inflammation is the underlying common mechanism involved in CVD. It has been recently …

Background & Aims Population-based studies have suggested an increased risk of acute
arterial events (AAEs) in patients with inflammatory bowel disease (IBD). We aimed to …

Inflammatory bowel diseases (IBD) are often associated with dysregulated gut microbiota
and excessive inflammatory microenvironment. Probiotic therapy combined with …

Although high-fat diet (HFD)-induced gut microbiota dysbiosis is known to affect
atherosclerosis, the underlying mechanisms remain to be fully explored. Here, we show that …

Inflammatory bowel disease is associated with intestinal homeostasis dysregulation and gut
microbiota dysbiosis. This study aimed to investigate the protective effect of Ganoderma …

Background Activation of NLRP3 inflammasome accelerates the formation of atherosclerotic
plaques. Here, we evaluated the effects of inflammation on the expression of the NLRP3 …