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Peptide‐based supramolecular therapeutics for fighting major diseases
Z Wang, H Luo, H Wang, M **ao, H Jia… - Advanced Functional …, 2024 - Wiley Online Library
Peptide‐based supramolecular therapeutics (PST) refer to those theranostic nanomedicines
based on peptide or peptide derivatives self‐assembly that are constructed in vitro or in vivo …
based on peptide or peptide derivatives self‐assembly that are constructed in vitro or in vivo …
Imaging-guided targeted radionuclide tumor therapy: from concept to clinical translation
J Sun, Z Huangfu, J Yang, G Wang, K Hu, M Gao… - Advanced Drug Delivery …, 2022 - Elsevier
Since the first introduction of sodium iodide I-131 for use with thyroid patients almost 80
years ago, more than 50 radiopharmaceuticals have reached the markets for a wide range …
years ago, more than 50 radiopharmaceuticals have reached the markets for a wide range …
Dendrimers based cancer nanotheranostics: An overview
Cancer is a known deadliest disease that requires a judicious diagnostic, targeting, and
treatment strategy for an early prognosis and selective therapy. The major pitfalls of the …
treatment strategy for an early prognosis and selective therapy. The major pitfalls of the …
An Overview of In Vitro Assays of 64Cu-, 68Ga-, 125I-, and 99mTc-Labelled Radiopharmaceuticals Using Radiometric Counters in the Era of Radiotheranostics
Radionuclides are unstable isotopes that mainly emit alpha (α), beta (β) or gamma (γ)
radiation through radiation decay. Therefore, they are used in the biomedical field to label …
radiation through radiation decay. Therefore, they are used in the biomedical field to label …
EANM position paper on the role of radiobiology in nuclear medicine
A Aerts, U Eberlein, S Holm, R Hustinx… - European journal of …, 2021 - Springer
With an increasing variety of radiopharmaceuticals for diagnostic or therapeutic nuclear
medicine as valuable diagnostic or treatment option, radiobiology plays an important role in …
medicine as valuable diagnostic or treatment option, radiobiology plays an important role in …
Immunological effects of radiopharmaceutical therapy
AG Shea, MB Idrissou, AI Torres, T Chen… - Frontiers in Nuclear …, 2024 - frontiersin.org
Radiation therapy (RT) is a pillar of cancer therapy used by more than half of all cancer
patients. Clinically, RT is mostly delivered as external beam radiation therapy (EBRT) …
patients. Clinically, RT is mostly delivered as external beam radiation therapy (EBRT) …
Novel CDK19-Targeted Radiotracers: A Potential Design Strategy to Improve the Pharmacokinetics and Tumor Uptake
D Dai, J Yu, W Gou, S Yang, Y Li, Z Wang… - Journal of Medicinal …, 2024 - ACS Publications
Cyclin-dependent kinase 19 (CDK19) is overexpressed in prostate cancer, making it an
attractive target for both imaging and therapy. Since little is known about the optimized …
attractive target for both imaging and therapy. Since little is known about the optimized …
Targeted radionuclide therapy: an emerging field in solid tumours
Recent research has demonstrated and consolidated the use of TRNT against well
established targets in neuroendocrine tumours and prostate cancer. The identification of …
established targets in neuroendocrine tumours and prostate cancer. The identification of …
Computational nuclear oncology toward precision radiopharmaceutical therapies: current tools, techniques, and uncharted territories
Radiopharmaceutical therapy (RPT), with its targeted delivery of cytotoxic ionizing radiation,
demonstrates significant potential for treating a wide spectrum of malignancies, with …
demonstrates significant potential for treating a wide spectrum of malignancies, with …
Towards Improving the Efficacy of PSMA-Targeting Radionuclide Therapy for Late-Stage Prostate Cancer—Combination Strategies
D Arbuznikova, M Eder, AL Grosu, PT Meyer… - Current oncology …, 2023 - Springer
Abstract Purpose of Review [177Lu] Lu-PSMA-617 is a radiopharmaceutical that emits beta-
minus radiation and targets prostate-specific membrane antigen (PSMA)-positive prostate …
minus radiation and targets prostate-specific membrane antigen (PSMA)-positive prostate …