Peptide‐based supramolecular therapeutics for fighting major diseases

Z Wang, H Luo, H Wang, M **ao, H Jia… - Advanced Functional …, 2024 - Wiley Online Library
Peptide‐based supramolecular therapeutics (PST) refer to those theranostic nanomedicines
based on peptide or peptide derivatives self‐assembly that are constructed in vitro or in vivo …

Imaging-guided targeted radionuclide tumor therapy: from concept to clinical translation

J Sun, Z Huangfu, J Yang, G Wang, K Hu, M Gao… - Advanced Drug Delivery …, 2022 - Elsevier
Since the first introduction of sodium iodide I-131 for use with thyroid patients almost 80
years ago, more than 50 radiopharmaceuticals have reached the markets for a wide range …

Dendrimers based cancer nanotheranostics: An overview

V Saluja, Y Mishra, V Mishra, N Giri, P Nayak - International journal of …, 2021 - Elsevier
Cancer is a known deadliest disease that requires a judicious diagnostic, targeting, and
treatment strategy for an early prognosis and selective therapy. The major pitfalls of the …

An Overview of In Vitro Assays of 64Cu-, 68Ga-, 125I-, and 99mTc-Labelled Radiopharmaceuticals Using Radiometric Counters in the Era of Radiotheranostics

V Benfante, A Stefano, M Ali, R Laudicella, W Arancio… - Diagnostics, 2023 - mdpi.com
Radionuclides are unstable isotopes that mainly emit alpha (α), beta (β) or gamma (γ)
radiation through radiation decay. Therefore, they are used in the biomedical field to label …

EANM position paper on the role of radiobiology in nuclear medicine

A Aerts, U Eberlein, S Holm, R Hustinx… - European journal of …, 2021 - Springer
With an increasing variety of radiopharmaceuticals for diagnostic or therapeutic nuclear
medicine as valuable diagnostic or treatment option, radiobiology plays an important role in …

Immunological effects of radiopharmaceutical therapy

AG Shea, MB Idrissou, AI Torres, T Chen… - Frontiers in Nuclear …, 2024 - frontiersin.org
Radiation therapy (RT) is a pillar of cancer therapy used by more than half of all cancer
patients. Clinically, RT is mostly delivered as external beam radiation therapy (EBRT) …

Novel CDK19-Targeted Radiotracers: A Potential Design Strategy to Improve the Pharmacokinetics and Tumor Uptake

D Dai, J Yu, W Gou, S Yang, Y Li, Z Wang… - Journal of Medicinal …, 2024 - ACS Publications
Cyclin-dependent kinase 19 (CDK19) is overexpressed in prostate cancer, making it an
attractive target for both imaging and therapy. Since little is known about the optimized …

Targeted radionuclide therapy: an emerging field in solid tumours

C Artigas, M Mileva, P Flamen… - Current opinion in …, 2021 - journals.lww.com
Recent research has demonstrated and consolidated the use of TRNT against well
established targets in neuroendocrine tumours and prostate cancer. The identification of …

Computational nuclear oncology toward precision radiopharmaceutical therapies: current tools, techniques, and uncharted territories

T Yusufaly, E Roncali, J Brosch-Lenz… - Journal of Nuclear …, 2025 - jnm.snmjournals.org
Radiopharmaceutical therapy (RPT), with its targeted delivery of cytotoxic ionizing radiation,
demonstrates significant potential for treating a wide spectrum of malignancies, with …

Towards Improving the Efficacy of PSMA-Targeting Radionuclide Therapy for Late-Stage Prostate Cancer—Combination Strategies

D Arbuznikova, M Eder, AL Grosu, PT Meyer… - Current oncology …, 2023 - Springer
Abstract Purpose of Review [177Lu] Lu-PSMA-617 is a radiopharmaceutical that emits beta-
minus radiation and targets prostate-specific membrane antigen (PSMA)-positive prostate …