Malaria poses a severe public health risk and a significant economic burden in disease-
endemic countries. One of the most severe issues in malaria control is the development of …

Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …

Amongst heterocyclic compounds, quinoline and its derivatives are advantaged scaffolds
that appear as a significant assembly motif for develo** new drug entities. Aminoquinoline …

Malaria is the fifth most lethal parasitic infection in the world. Antimalarial medications have
played a crucial role in preventing and eradicating malaria. Numerous heterocyclic moieties …

In this 21 st century, Malaria remains a global burden and causes massive economic trouble
to disease-endemic nations. The control and eradication of malaria is a major challenge that …

Development and discovery of new antimalarial drugs are needed to overcome the multi-
resistance of Plasmodium parasites to commercially available drugs. Modifying the …

Malaria is a widespread infectious disease, causing nearly 247 million cases in 2021. The
absence of a broadly effective vaccine and rapidly decreasing effectiveness of most of the …

Despite much interest and studies toward the genus Podocarpus, the anti-malarial
evaluation of Podocarpus polystachyus's phytoconstituents remains lacking. Herein, the …

In this work, a series of nineteen novel pyrano [2, 3-c] pyrazole-4-aminoquinoline hybrids
were synthesized as potent antimalarial agents by covalently linking the scaffolds of 4 …

Malaria remains an important and challenging infectious disease, and novel antimalarials
are required. Benzyl isothiocyanate (BITC), the main breakdown product of benzyl …