[HTML][HTML] Understanding the pathophysiology of thrombotic APS through animal models

AA Gandhi, SK Estes, CE Rysenga… - International journal of …, 2021 - mdpi.com
Antiphospholipid syndrome (APS) is a leading acquired cause of thrombotic events, with a
notable tendency to promote thrombosis in vascular beds of all sizes, including both arterial …

Progress in the field of animal models of antiphospholipid syndrome

X Gao, D Ma, L Mi, J Zhao, Q An, Z Guo, B Yang… - …, 2024 - Taylor & Francis
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by recurrent
arteriovenous thrombosis and pathological pregnancy, accompanied by persistent …

Neutrophil extracellular traps formation may be involved in the association of propranolol with the development of portal vein thrombosis

X Xu, S Xu, Y Zhang, L Wang, C Yan, Z Xu, Q Zhao… - Thrombosis …, 2024 - Elsevier
Background & aims Nonselective β blockers (NSBBs) facilitate the development of portal
vein thrombosis (PVT) in liver cirrhosis. Considering the potential effect of NSBBs on …

Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi

C Duval, A Baranauskas, T Feller, M Ali… - Proceedings of the …, 2021 - pnas.org
The onset of venous thromboembolism, including pulmonary embolism, represents a
significant health burden affecting more than 1 million people annually worldwide. Current …

Resistance exercise promotes the resolution and recanalization of deep venous thrombosis in a mouse model via SIRT1 upregulation

C Wu, X Li, H Zhao, Y Ling, Y Ying, Y He… - BMC Cardiovascular …, 2023 - Springer
Background Early exercise for acute deep venous thrombosis (DVT) improves the patient's
symptoms and does not increase the risk of pulmonary embolism. However, information …

Mouse inferior vena cava stenosis model with all branches interrupted may help deep vein thrombosis research

L Wang, P Wang, F Zhang, X Guo, X Chen… - Journal of Thrombosis …, 2023 - jthjournal.org
Deep vein thrombosis (DVT) is a major cause of morbidity and mortality worldwide. Murine
models are critical tools for understanding the DVT mechanism and bridging the bench-to …

Nonthrombotic internal jugular venous stenosis may facilitate cerebral venous thrombosis

X Wu, J Ya, D Zhou, Y Ding, X Ji… - CNS Neuroscience & …, 2021 - Wiley Online Library
Aims To explore the effect of nonthrombotic internal jugular venous stenosis (IJVS) exerted
on cerebral venous thrombosis (CVT). Methods Patients with imaging confirmed CVT were …

[HTML][HTML] Basic science research opportunities in thrombosis and hemostasis: Communication from the SSC of the ISTH

NJ Mutch, S Walters, EE Gardiner, OJT McCarty… - Journal of Thrombosis …, 2022 - Elsevier
Bleeding and thrombosis are major clinical problems with high morbidity and mortality.
Treatment modalities for these diseases have improved in recent years, but there are many …

[HTML][HTML] Inferior vena cava stenosis-induced deep vein thrombosis is influenced by multiple factors in rats

H Liu, Z Lu, B Lin, JY Zhan, S Gui, W Chen… - Biomedicine & …, 2020 - Elsevier
Background The pathogenesis of deep vein thrombosis (DVT) is incompletely understood,
requiring reliable animal models. Inferior vena cava (IVC) stenosis model mimics human …

Establishment and application of animal models for portal vein thrombosis

LIU Zhuang, C Jihong, QI **ngshun, XU **angbo… - 临床肝胆病杂志, 2024 - lcgdbzz.com
Portal vein thrombosis (PVT) refers to thromboembolism that occurs in the extrahepatic main
portal vein and/or intrahepatic portal vein branches. PVT is the result of the combined effect …