[HTML][HTML] Bioactive compounds from nature: Antioxidants targeting cellular transformation in response to epigenetic perturbations induced by oxidative stress

A Bouyahya, S Bakrim, S Aboulaghras… - Biomedicine & …, 2024 - Elsevier
Oxidative stress results from a persistent imbalance in oxidation levels that promotes
oxidants, playing a crucial role in the early and sustained phases of DNA damage and …

Hepatocellular carcinoma and lipid metabolism: novel targets and therapeutic strategies

LQ Cao, Y **e, JS Fleishman, X Liu, ZS Chen - Cancer letters, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is an increasingly prevalent disease that is associated with
high and continually rising mortality rates. Lipid metabolism holds a crucial role in the …

Metformin and the liver: unlocking the full therapeutic potential

F Perazza, L Leoni, S Colosimo, A Musio, G Bocedi… - Metabolites, 2024 - mdpi.com
Metformin is a highly effective medication for managing type 2 diabetes mellitus. Recent
studies have shown that it has significant therapeutic benefits in various organ systems …

Metabolism changes caused by glucose in normal and cancer human brain cell lines by Raman imaging and chemometric methods

M Kopec, K Beton-Mysur, J Surmacki, H Abramczyk - Scientific Reports, 2024 - nature.com
Glucose is the main source of energy for the human brain. This paper presents a non-
invasive technique to study metabolic changes caused by glucose in human brain cell lines …

Liver cancer etiology: old issues and new perspectives

JG Chen, YH Zhang, JH Lu, TW Kensler - Current Oncology Reports, 2024 - Springer
Abstract Purpose of Review This review aims to synthesize the old issues and current
understandings of the etiology of liver cancer, focusing on the diverse causative factors …

Susceptibility of diabetic patients to COVID-19 infections: Clinico-hematological and complications analysis

B Atwah, MS Iqbal, S Kabrah, A Kabrah, S Alghamdi… - Vaccines, 2023 - mdpi.com
Background: Coronavirus disease 2019 has become a global health threat resulting in a
catastrophic spread and more than 3.8 million deaths worldwide. It has been suggested that …

The dichloromethane fraction from Calotropis gigantea (L.) dryand. Stem bark extract prevents liver cancer in SDT rats with insulin-independent diabetes mellitus

T Haewphet, S Parhira, P Chaisupasakul… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Calotropis gigantea (L.) Dryand.(C. gigantea) is a
traditional medicinal plant, recognized for its effectiveness in managing diabetes, along with …

Ensemble learning enhances the precision of preliminary detection of primary hepatocellular carcinoma based on serological and demographic indices

M Wang, B Zhuang, S Yu, G Li - Frontiers in Oncology, 2024 - pmc.ncbi.nlm.nih.gov
Primary hepatocellular carcinoma (PHC) is associated with high rates of morbidity and
malignancy in China and throughout the world. In clinical practice, a combination of …

Combined effects of smoking and alcohol consumption on the risk of liver cancer according to metabolic syndrome: A nested case–control study in South Korea

TT Bui, E Park, HY Kang, JK Oh - International Journal of …, 2024 - Wiley Online Library
Tobacco and alcohol may interact to increase the risk of liver cancer, which might be
modified by other risk factors. Their combined effects in the context of metabolic syndrome …

[HTML][HTML] Development of a Prediction Model and Risk Score for Self-Assessment and High-Risk Population Identification in Liver Cancer Screening: Prospective …

X Li, Y Wang, H Li, L Wang, J Zhu… - JMIR Public Health …, 2024 - publichealth.jmir.org
Background Liver cancer continues to pose a significant burden in China. To enhance the
efficiency of screening, it is crucial to implement population stratification for liver cancer …