With the success of immune checkpoint inhibitors (ICIs), significant progress has been made
in the field of cancer immunotherapy. Despite the long-lasting outcomes in responders, the …

Breast cancer (BC) is the main cause of cancer-related mortality among women globally.
Despite substantial advances in the identification and management of primary tumors …

Background Osteosarcoma (OS) is the most common malignant bone tumor and has a poor
prognosis. The potential involvement of circular RNAs (circRNAs) in OS progression …

Cancer evolution is a complex process influenced by genetic factors and extracellular stimuli
that trigger signaling pathways to coordinate the continuous and dynamic interaction …

Breast cancer (BC) is the most frequently invasive malignancy and the leading cause of
tumor-related mortality among women worldwide. Cancer metastasis is a complex …

Tumor cell plasticity exhibited as an epithelial–mesenchymal transition (EMT) has been
identified as a major obstacle for the effective treatment of many cancers. This process …

Lactate dehydrogenase A (LDHA), a critical component of the glycolytic pathway, relates to
the development of various cancers, including thyroid cancer. However, the regulatory …

Glioblastoma (GBM) tumors are the most aggressive primary brain tumors in adults that,
despite maximum treatment, carry a dismal prognosis. GBM tumors exhibit tissue hypoxia …

Simple Summary Autophagy is a self-eating mechanism that is involved in the degradation
of organelles and cellular materials. It is initiated by intracellular and extracellular stress …

Cancer-associated fibroblasts (CAFs) and hypoxia are central players in the complex
process of tumor cell-stroma interaction and are involved in the alteration of the anti-tumor …