Cardiorenal syndrome encompasses a spectrum of disorders involving both the heart and
kidneys in which acute or chronic dysfunction in 1 organ may induce acute or chronic …

The vast majority of acute heart failure episodes are characterized by increasing symptoms
and signs of congestion with volume overload. The goal of therapy in those patients is the …

Measurement of natriuresis has been suggested as a reliable, easily obtainable biomarker
for assessment of the response to diuretic treatment in patients with acute heart failure …

Sodium and fluid restriction has traditionally been advocated in patients with heart failure
(HF) due to their sodium and water avid state. However, most evidence regarding the altered …

The administration of loop diuretics to achieve decongestion is the cornerstone of therapy for
acute heart failure. Unfortunately, impaired response to diuretics is common in these …

Increased neurohumoral stimulation resulting in excessive sodium avidity and extracellular
volume overload are hallmark features of decompensated heart failure. Especially in case of …

This discussion is focused on the interactions during acute and chronic heart failure (HF)
between heart and kidney, which are highly interdependent in health and disease. In normal …

Aims Urinary sodium assessment has recently been proposed as a target for loop diuretic
therapy in acute heart failure (AHF). We aimed to investigate the time course, clinical …

Aims Insufficient diuretic response frequently occurs in patients admitted for acute heart
failure (HF) and is associated with worse clinical outcomes. Recent studies have shown that …

Aims The clinical significance of the measurement of urine sodium concentration (UNa+) in
response to loop diuretic administration in patients with acute heart failure (AHF) is still …