The decreasing cost of sequencing and concomitant augmentation of publicly available
genomes have created an acute need for automated software to assess genomic …

The Bacillus cereus group, also known as B. cereus sensu lato (sl), is a species complex
that contains numerous closely related lineages, which vary in their ability to cause illness in …

Much of the complexity within cells arises from functional and regulatory interactions among
proteins. The core of these interactions is increasingly known, but novel interactions …

Background Recent evidence suggests a role for the microbiome in pancreatic ductal
adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and …

Even though automated functional annotation of genes represents a fundamental step in
most genomic and metagenomic workflows, it remains challenging at large scales. Here, we …

Heterotrophic bacteria—bacteria that utilize organic carbon sources—are taxonomically and
functionally diverse across environments. It is challenging to map metabolic interactions and …

Natural microbial communities are phylogenetically and metabolically diverse. In addition to
underexplored organismal groups, this diversity encompasses a rich discovery potential for …

Microbial genes encode the majority of the functional repertoire of life on earth. However,
despite increasing efforts in metagenomic sequencing of various habitats,–, little is known …

Fecal microbiota transplantation (FMT) is a therapeutic intervention for inflammatory
diseases of the gastrointestinal tract, but its clinical mode of action and subsequent …

The eggNOG (evolutionary gene genealogy Non-supervised Orthologous Groups) database
is a bioinformatics resource providing orthology data and comprehensive functional …