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A systematic review of multimodal brain age studies: Uncovering a divergence between model accuracy and utility
Brain aging is a complex, multifaceted process that can be challenging to model in ways that
are accurate and clinically useful. One of the most common approaches has been to apply …
are accurate and clinically useful. One of the most common approaches has been to apply …
[HTML][HTML] A review of the pathology and treatment of TBI and PTSD
This literature review focuses on the underlying pathophysiology of TBI and PTSD
symptoms, while also examining the plethora of stem cell treatment options to ameliorate …
symptoms, while also examining the plethora of stem cell treatment options to ameliorate …
Sex-based contributors to and consequences of post-traumatic stress disorder
Abstract Purpose of Review Women are twice as likely to develop post-traumatic stress
disorder (PTSD) compared to men after a traumatic experience. The purpose of this mini …
disorder (PTSD) compared to men after a traumatic experience. The purpose of this mini …
Brain age prediction using combined deep convolutional neural network and multi-layer perceptron algorithms
Y Joo, E Namgung, H Jeong, I Kang, J Kim, S Oh… - Scientific Reports, 2023 - nature.com
The clinical applications of brain age prediction have expanded, particularly in anticipating
the onset and prognosis of various neurodegenerative diseases. In the current study, we …
the onset and prognosis of various neurodegenerative diseases. In the current study, we …
Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study
AZ Wagen, W Coath, A Keshavan… - The Lancet Healthy …, 2022 - thelancet.com
Background A neuroimaging-based biomarker termed the brain age is thought to reflect
variability in the brain's ageing process and predict longevity. Using Insight 46, a unique …
variability in the brain's ageing process and predict longevity. Using Insight 46, a unique …
[HTML][HTML] Brain-age is associated with progression to dementia in memory clinic patients
Background Biomarkers for the early detection of dementia risk hold promise for better
disease monitoring and targeted interventions. However, most biomarker studies …
disease monitoring and targeted interventions. However, most biomarker studies …
Association of maternal depression during pregnancy and recent stress with brain age among adult offspring
K Mareckova, R Mareček, M Jani, L Zackova… - JAMA Network …, 2023 - jamanetwork.com
Importance Maternal mental health problems during pregnancy are associated with altered
neurodevelopment in offspring, but the long-term relationship between these prenatal risk …
neurodevelopment in offspring, but the long-term relationship between these prenatal risk …
[HTML][HTML] Advanced brain ageing in adult psychopathology: A systematic review and meta-analysis of structural MRI studies
Evidence suggests that psychopathology is associated with an advanced brain ageing
process, typically mapped using machine learning models that predict an individual's age …
process, typically mapped using machine learning models that predict an individual's age …
Advanced brain-age in psychotic psychopathology: evidence for transdiagnostic neurodevelopmental origins
Schizophrenia is characterized by abnormal brain structure such as global reductions in
gray matter volume. Machine learning models trained to estimate the age of brains from …
gray matter volume. Machine learning models trained to estimate the age of brains from …
Epigenetic aging mediates the association between pain impact and brain aging in middle to older age individuals with knee pain
Chronic musculoskeletal pain is a health burden that may accelerate the aging process.
Accelerated brain aging and epigenetic aging have separately been observed in those with …
Accelerated brain aging and epigenetic aging have separately been observed in those with …