Recent advances in Garratt-Braverman cyclization: Mechanistic and synthetic explorations

P Bhattacharya, M Singha, E Das, A Mandal, M Maji… - Tetrahedron …, 2018 - Elsevier
Garratt-Braverman cyclization has emerged as one of the simplest synthetic tool to construct
two consecutive Csingle bondC bonds leading to the formation of various important …

Exploring Diradical Chemistry: A Carbon‐Centered Radical May Act as either an Anion or Electrophile through an Orbital Isomer

TP Gonçalves, M Mohamed, RJ Whitby… - Angewandte Chemie …, 2015 - Wiley Online Library
Diradical intermediates, formed by thermolysis of alkynylcyclobutenones, can display
radical, anion, or electrophilic character because of the existence of an orbital isomer with …

Synthesis of benzochromenes and dihydrophenanthridines with helical motifs using Garratt–Braverman and Buchwald–Hartwig reactions

P Bhattacharya, K Senapati, K Chattopadhyay… - RSC …, 2015 - pubs.rsc.org
A simple strategy for the synthesis of 6H-benzo [c] chromenes and 5, 6-
dihydrophenanthridines through a judicious use of Garratt–Braverman (GB) cyclization and …

A Garratt-Braverman cyclization route towards the synthesis of phenanthridine derivatives and their DNA-binding studies

A Mandal, P Bhattacharya, AK Das, A Basak - Tetrahedron, 2019 - Elsevier
Garratt-Braverman cyclization has been employed to synthesize a series of dihydroisofuran
fused phenanthridine derivatives. The established protocol proposes a simpler synthetic …

Shifting the reactivity of bis-propargyl ethers from garratt–braverman cyclization mode to 1, 5-H shift pathway to yield 3, 4-disubstituted furans: a combined …

J Das, E Das, S Jana, PS Addy, A Anoop… - The Journal of Organic …, 2016 - ACS Publications
Aryl or vinyl substituted bis-propargyl ethers upon base treatment generally form phthalans
via the Garratt–Braverman (GB) cyclization pathway. In a major departure from this usual …

Does the Mechanism of the Garratt–Braverman Cyclization Differ with Substrates? A Computational Study on Bispropargyl Sulfones, Sulfides, Ethers, Amines, and …

S Jana, A Anoop - The Journal of Organic Chemistry, 2016 - ACS Publications
We studied the variation in mechanism among different bispropargyl substrates sulfone,
sulfide, ether, amine, and methane toward Garratt–Braverman (GB) cyclization using …

A Garratt-Braverman route to isoindolines and phthalans

M Singha, M Maji, M Gupta, S Majhi, A Basak - Tetrahedron Letters, 2019 - Elsevier
Abstract Garratt-Braverman (GB) cyclization, two Csingle bondC bond forming reaction in a
single step, has been utilized to construct several isoindoline and phthalan derivatives. The …

Sonogashira coupling and Garratt–Braverman cyclization in tandem: formation of four C–C bonds leading to the synthesis of aryl dihydro isofurans and isoindoles

D Ghosh, P Pal, A Basak - Tetrahedron letters, 2015 - Elsevier
In this Letter we report an interesting one pot synthesis of aryl dihydro isofurans and
isoindoles, naturally occurring privileged skeletons, in excellent yields from easily …

Effect of π–π interaction in Bergman cyclisation

S Jana, A Anoop - Physical Chemistry Chemical Physics, 2015 - pubs.rsc.org
The role of π–π interactions in controlling the reactivity and selectivity of a chemical reaction
is only recently being explored, even though their ubiquitous role in the structural aspects is …

Synthesis of DNA‐Intercalating 6H‐Benzo[c]chromen‐6‐one Derivatives through a Strategic Combination of Garratt–Braverman and Minisci Acyloxylation Reactions

P Bhattacharya, SM Mandal… - European Journal of …, 2016 - Wiley Online Library
A new strategy for the synthesis of 6H‐benzo [c] chromen‐6‐ones through judicious use of
Garratt–Braverman (GB) Cyclization and Minisci acyloxylation reactions in moderate to good …